4-amino-5-[2-(N-methylamino)phenyl]-3-mercapto-1,2,4-triazole

Base Information

• Chemical Name: 4-amino-5-[2-(N-methylamino)phenyl]-3-mercapto-1,2,4-triazole
• CAS No.: 914978-98-6
• Molecular Formula: C₉H₁₁N₅S
• Molecular Weight: 221.286
• Mol file: 914978-98-6.mol

Synonyms:4-amino-5-[2-(N-methylamino)phenyl]-3-mercapto-1,2,4-triazole

Chemical Property of 4-amino-5-[2-(N-methylamino)phenyl]-3-mercapto-1,2,4-triazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-amino-5-[2-(N-methylamino)phenyl]-3-mercapto-1,2,4-triazole

There total 1 articles about 4-amino-5-[2-(N-methylamino)phenyl]-3-mercapto-1,2,4-triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

carbon disulfide (75-15-0,12122-00-8) + 1-(2-methylaminobenzoyl)hydrazine (52479-65-9) → 4-amino-5-[2-(N-methylamino)phenyl]-3-mercapto-1,2,4-triazole (914978-98-6)

Guidance literature:

carbon disulfide; 1-(2-methylaminobenzoyl)hydrazine; With potassium hydroxide; In ethanol; for 15h;

With hydrazine hydrate; In water; Heating;

DOI:10.1016/j.ejmech.2006.03.018

Reference yield: 64.0%

4-amino-5-[2-(N-methylamino)phenyl]-3-mercapto-1,2,4-triazole (914978-98-6) + 2-(2,4-dichlorophenoxy)propionic acid (120-36-5) → 3-[2-(N-methylamino)phenyl]-6-[1-(2,4-dichlorophenoxy)ethyl]-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole

Guidance literature:

With trichlorophosphate; for 4h; Heating;

DOI:10.1016/j.ejmech.2006.03.018

Reference yield: 60.0%

4-amino-5-[2-(N-methylamino)phenyl]-3-mercapto-1,2,4-triazole (914978-98-6) + cinchophen (132-60-5) → methyl-{2-[6-(2-phenyl-quinolin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl]-phenyl}-amine

Guidance literature:

With trichlorophosphate; for 7h; Heating;

DOI:10.1016/j.ejmech.2006.03.018

upstream raw materials:

carbon disulfide

1-(2-methylaminobenzoyl)hydrazine

Downstream raw materials:

3-(2-(N-methylamino)phenyl)-6-(1H-pyrrol-2-yl)-5,6-dihydro-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole

3-(4-(N-methylamino)phenyl)-6-[2-furanyl]-5,6-dihydro-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole

3-(2-(N-methylamino)phenyl)-6-(1-methyl-pyrrol-2-yl)-5,6-dihydro-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole

3-(2-(N-methylamino)phenyl)-6-[5-chloro-2-furanyl]-5,6-dihydro-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole