1-[3-(4-Hydroxyphenyl)-propyl]-2-mercaptoimidazole

Base Information

Chemical Name:1-[3-(4-Hydroxyphenyl)-propyl]-2-mercaptoimidazole
CAS No.:95333-65-6
Molecular Formula:C₁₂H₁₄N₂OS
Molecular Weight:234.322
Hs Code.:
ChEMBL ID:CHEMBL350128
DSSTox Substance ID:DTXSID801175090
Nikkaji Number:J273.623C

Synonyms:CHEMBL350128;95333-65-6;1-[3-(4-hydroxyphenyl)-propyl]-2-mercaptoimidazole;SCHEMBL9837787;CUGJJJHGRSSKCA-UHFFFAOYSA-N;DTXSID801175090;BDBM50014962;4-[3-(2-Mercapto-imidazol-1-yl)-propyl]-phenol;1,3-Dihydro-1-[3-(4-hydroxyphenyl)propyl]-2H-imidazole-2-thione;1-[3-(4-Hydroxy-phenyl)-propyl]-1,3-dihydro-imidazole-2-thione

Suppliers and Price of 1-[3-(4-Hydroxyphenyl)-propyl]-2-mercaptoimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-[3-(4-Hydroxyphenyl)-propyl]-2-mercaptoimidazole

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:234.08268425
Heavy Atom Count:16
Complexity:272

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1CCCN2C=CNC2=S)O

Technology Process of 1-[3-(4-Hydroxyphenyl)-propyl]-2-mercaptoimidazole

There total 6 articles about 1-[3-(4-Hydroxyphenyl)-propyl]-2-mercaptoimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 95333-89-4
1-<3-(4-methoxyphenyl)-propyl>imidazole-2-thione

: 95333-65-6
1-[3-(4-hydroxyphenyl)propyl]imidazole-2-thione

Guidance literature:: With boron tribromide; In dichloromethane; for 1.5h; Ambient temperature;
DOI:10.1021/jm00162a008

Reference yield:

: 95333-89-4
1-[3-(4-Methoxyphenyl)-propyl]-2-mercaptoimidazole

: 95333-65-6
1-[3-(4-Hydroxyphenyl)propyl]-2-mercaptoimidazole

Guidance literature:: With boron tribromide; In dichloromethane;

Reference yield:

: 1929-29-9
3-(4-methoxyphenyl)propanoic acid

: 95333-65-6
1-[3-(4-hydroxyphenyl)propyl]imidazole-2-thione

Guidance literature:: Multi-step reaction with 5 steps

1: oxalyl chloride, pyridine / CH₂Cl₂ / 2.5 h

2: CH₂Cl₂ / 5 - 20 °C

3: 52 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 3.5 h / 22 °C

4: 69 percent / aq. 3 N HCl / ethanol / 5 h / Heating

5: 67 percent / BBr₃ / CH₂Cl₂ / 1.5 h / Ambient temperature

With pyridine; hydrogenchloride; lithium aluminium tetrahydride; oxalyl dichloride; boron tribromide; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane;
DOI:10.1021/jm00162a008