C₁₅H₁₉NO₃

Base Information

• Chemical Name: C₁₅H₁₉NO₃
• CAS No.: 1414976-32-1
• Molecular Formula: C₁₅H₁₉NO₃
• Molecular Weight: 261.321
• Mol file: 1414976-32-1.mol

Synonyms:C₁₅H₁₉NO₃

Chemical Property of C₁₅H₁₉NO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₅H₁₉NO₃

There total 9 articles about C₁₅H₁₉NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

C15H19NO3 (1414976-30-9) → C15H19NO3 (1414976-32-1)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In methanol; at 20 ℃; for 22h;

Reference yield:

1-cyclopentene-1-carboxaldehyde (6140-65-4) → C15H19NO3 (1414976-32-1)

Guidance literature:

Multi-step reaction with 6 steps

1: acetic acid; (S)-2-(diphenyltrimethylsilyloxymethyl)proline / water; methanol / 25 h

2: toluene-4-sulfonic acid / methanol; tert-butyl methyl ether / 24 h / 25 °C

3: hydrogen; 20% palladium hydroxide-activated charcoal / methanol / 2.5 h / 27 °C / 3750.38 Torr

4: potassium carbonate / water; tert-butyl methyl ether / 18 h / 0 - 20 °C

5: hydrogenchloride / water; tetrahydrofuran / 20 h / 20 °C

6: 1,8-diazabicyclo[5.4.0]undec-7-ene / methanol / 22 h / 20 °C

With hydrogenchloride; 20% palladium hydroxide-activated charcoal; (S)-2-(diphenyltrimethylsilyloxymethyl)proline; hydrogen; potassium carbonate; toluene-4-sulfonic acid; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; methanol; tert-butyl methyl ether; water;

Reference yield:

1,6-hexanediol (629-11-8) → C15H19NO3 (1414976-32-1)

Guidance literature:

Multi-step reaction with 7 steps

1.1: potassium bromide; sodium hydrogencarbonate; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hypochlorite / chloroform; water / 4.67 h / 2 - 10 °C

1.2: 12 h / 40 - 45 °C

2.1: acetic acid; (S)-2-(diphenyltrimethylsilyloxymethyl)proline / water; methanol / 25 h

3.1: toluene-4-sulfonic acid / methanol; tert-butyl methyl ether / 24 h / 25 °C

4.1: hydrogen; 20% palladium hydroxide-activated charcoal / methanol / 2.5 h / 27 °C / 3750.38 Torr

5.1: potassium carbonate / water; tert-butyl methyl ether / 18 h / 0 - 20 °C

6.1: hydrogenchloride / water; tetrahydrofuran / 20 h / 20 °C

7.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / methanol / 22 h / 20 °C

With hydrogenchloride; sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; 20% palladium hydroxide-activated charcoal; (S)-2-(diphenyltrimethylsilyloxymethyl)proline; hydrogen; sodium hydrogencarbonate; potassium carbonate; toluene-4-sulfonic acid; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; potassium bromide; In tetrahydrofuran; methanol; tert-butyl methyl ether; chloroform; water;

upstream raw materials:

(1R,2R)-1-(dimethoxymethyl)-2-(nitromethyl)cyclopentane

C₉H₁₇NO₂

C₉H₁₉NO₂

C₁₇H₂₃NO₄

Downstream raw materials:

(1R,3aR,6aS)-octahydrocyclopenta[c]pyrrole-1-carbonitrile

(1S,3aR,6aS)-octahydrocyclopenta[c]pyrrole-1-carbonitrile