(R,R)-(+)-N,N'-Bis(alpha-methylbenzyl)sulfamide

Base Information

Chemical Name:(R,R)-(+)-N,N'-Bis(alpha-methylbenzyl)sulfamide
CAS No.:91410-68-3
Molecular Formula:C16H20 N2 O2 S
Molecular Weight:304.41
Hs Code.:
DSSTox Substance ID:DTXSID10350785
Nikkaji Number:J236.298H
Wikidata:Q82126887
Mol file:91410-68-3.mol

Synonyms:91410-68-3;(R,R)-(+)-N,N'-Bis(alpha-methylbenzyl)sulfamide;(1R)-1-phenyl-N-[[(1R)-1-phenylethyl]sulfamoyl]ethanamine;N,N'-BIs[(1R)-1-phenylethyl]sulfamide;(R,R)-(+)-N,N'-Bis(alfa-methylbenzyl)sulfamide;ZUMVQOILJDLACR-ZIAGYGMSSA-;DTXSID10350785;n,n'-sulfonyl bis[(r)-1-phenyl-ethylamine];J-016724;(R,R)-(+)-N,N'-Bis( alpha -methylbenzyl)sulfamide;(R,R)-(+)-N,N'-Bis(.alpha.-methylbenzyl)sulfamide;(R,R)-(+)-N,N'-Bis(alpha-methylbenzyl)sulfamide, 99%;InChI=1/C16H20N2O2S/c1-13(15-9-5-3-6-10-15)17-21(19,20)18-14(2)16-11-7-4-8-12-16/h3-14,17-18H,1-2H3/t13-,14-/m1/s1

Suppliers and Price of (R,R)-(+)-N,N'-Bis(alpha-methylbenzyl)sulfamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(R,R)-(+)-N,N′-Bis(α-methylbenzyl)sulfamide 99%
5g
$ 123.00

American Custom Chemicals Corporation
(R,R)-(+)-N,N'-BIS(ALPHA-METHYLBENZYL)SULFAMIDE 99.00%
5G
$ 908.60

Total 6 raw suppliers

Chemical Property of (R,R)-(+)-N,N'-Bis(alpha-methylbenzyl)sulfamide

Chemical Property:

Melting Point:98-100 °C(lit.)
Boiling Point:450.2°Cat760mmHg
Flash Point:226.1°C
PSA：66.58000
Density:1.188g/cm³
LogP:4.79540
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:304.12454906
Heavy Atom Count:21
Complexity:361

Purity/Quality:

97% ^*data from raw suppliers

(R,R)-(+)-N,N′-Bis(α-methylbenzyl)sulfamide 99% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=CC=C1)NS(=O)(=O)NC(C)C2=CC=CC=C2
Isomeric SMILES:C[C@H](C1=CC=CC=C1)NS(=O)(=O)N[C@H](C)C2=CC=CC=C2

Technology Process of (R,R)-(+)-N,N'-Bis(alpha-methylbenzyl)sulfamide

There total 1 articles about (R,R)-(+)-N,N'-Bis(alpha-methylbenzyl)sulfamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 3886-69-9
(R)-1-phenyl-ethyl-amine

: 91410-68-3
N,N'-sulfonyl bis-[(R)-1-phenyl-ethylamine]

Guidance literature:: With sulfuryl dichloride; triethylamine; In dichloromethane; at 0 - 20 ℃; for 3h;
DOI:10.1016/S0040-4020(00)00885-1

Reference yield: 99.0%

: 91410-68-3
N,N'-sulfonyl bis-[(R)-1-phenyl-ethylamine]

: 106-95-6
allyl bromide

: 323178-13-8
N,N'-bis(2-propenyl)-N,N'-sulfonyl bis[(R)-1-phenylethylamine]

Guidance literature:: With potassium carbonate; In acetonitrile; at 70 ℃; for 14h;
DOI:10.1016/S0040-4020(00)00885-1

Reference yield:

: 91410-68-3
N,N'-sulfonyl bis-[(R)-1-phenyl-ethylamine]

: 1,1'-(1R,1'R)-[(2,3,6,7-tetrahydro-1,2,7-thiadiazepine-1,1-dioxido-2,7-diyl)]-1,1'-diphenylethane

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / K₂CO₃ / acetonitrile / 14 h / 70 °C

2: 94 percent / RuCl₂(Cy₃P)2CHPh / CH₂Cl₂ / 1.5 h / Heating

With Grubbs catalyst first generation; potassium carbonate; In dichloromethane; acetonitrile; 1: Alkylation / 2: ring-closing metathesis;
DOI:10.1016/S0040-4020(00)00885-1