2,5-anhydro-3-C-L-lyxose diethylacetal

Base Information

• Chemical Name: 2,5-anhydro-3-C-L-lyxose diethylacetal
• CAS No.: 79493-11-1
• Molecular Formula: C₂₂H₂₈O₄S₂
• Molecular Weight: 420.594
• Mol file: 79493-11-1.mol

Synonyms:2,5-anhydro-3-C-L-lyxose diethylacetal

Chemical Property of 2,5-anhydro-3-C-L-lyxose diethylacetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,5-anhydro-3-C-L-lyxose diethylacetal

There total 3 articles about 2,5-anhydro-3-C-L-lyxose diethylacetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-anhydro-3-O-benzoyl-4-O-tosyl-D-xylose diethylacetal (79493-09-7) → 2,5-anhydro-3-C-L-lyxose diethylacetal (79493-11-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / Br₂, methanolate de sodium / methanol / 2 h / Ambient temperature

2: hexamethylphosphoric acid triamide; tetrahydrofuran / 0 °C

With bromine; sodium methylate; In tetrahydrofuran; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide;

DOI:10.1016/S0040-4020(01)98932-X

Reference yield:

anion of bis(phenylthio)methane (70626-89-0) + 2,5;3,4-dianhydro-L-ribose diethylacetal (79493-12-2) → 2,5-anhydro-3-C-L-lyxose diethylacetal (79493-11-1)

Guidance literature:

In tetrahydrofuran; at 0 ℃; Yield given. Yields of byproduct given;

DOI:10.1016/S0040-4020(01)98932-X

Reference yield:

anion of bis(phenylthio)methane (70626-89-0) + 2,5;3,4-dianhydro-L-arabinose diethylacetal (79184-22-8) → 2,5-anhydro-3-C-L-lyxose diethylacetal (79493-11-1) + 2,5-anhydro-4-C-D-xylose diethylacetal (79493-10-0)

Guidance literature:

In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; at 0 ℃; Yield given. Yields of byproduct given;

DOI:10.1016/S0040-4020(01)98932-X

upstream raw materials:

anion of bis(phenylthio)methane

2,5;3,4-dianhydro-L-ribose diethylacetal

2,5;3,4-dianhydro-L-arabinose diethylacetal

2,5-anhydro-3-O-benzoyl-4-O-tosyl-D-xylose diethylacetal

Downstream raw materials:

1-C-<3'-O-acetyl-2'-desoxy-2'-C-bis(phenylthio)methyl-α-L-threofuranosyl>-3-oxo-oct-1-ene, trans

2,5-anhydro-4-O-acetyl-3-desoxy-3-C-L-lyxose

2,5-anhydro-4-O-acetyl-3-desoxy-3-C-L-lyxose diethylacetal