C₂₆H₃₂N₂O₄

Base Information

• Chemical Name: C₂₆H₃₂N₂O₄
• CAS No.: 1374109-41-7
• Molecular Formula: C₂₆H₃₂N₂O₄
• Molecular Weight: 436.551
• Mol file: 1374109-41-7.mol

Synonyms:C₂₆H₃₂N₂O₄

Chemical Property of C₂₆H₃₂N₂O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₃₂N₂O₄

There total 3 articles about C₂₆H₃₂N₂O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

C13H14ClNO2 (1374109-24-6) + C19H30BNO4 (1078137-78-6) → C26H32N2O4 (1374109-41-7)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; at 80 ℃; for 16h; Inert atmosphere;

Reference yield:

quinoline-2,6-diol (19315-93-6) → C26H32N2O4 (1374109-41-7)

Guidance literature:

Multi-step reaction with 3 steps

1: thionyl chloride; N,N-dimethyl-formamide / 16 h / 20 °C / Cooling with ice

2: pyridinium p-toluenesulfonate / tetrahydrofuran / 2.5 h / 20 °C

3: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / 16 h / 80 °C / Inert atmosphere

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; thionyl chloride; pyridinium p-toluenesulfonate; potassium carbonate; N,N-dimethyl-formamide; In tetrahydrofuran;

Reference yield:

6-hydroxy-2-chloroquinoline (577967-89-6) → C26H32N2O4 (1374109-41-7)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridinium p-toluenesulfonate / tetrahydrofuran / 2.5 h / 20 °C

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / 16 h / 80 °C / Inert atmosphere

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; pyridinium p-toluenesulfonate; potassium carbonate; In tetrahydrofuran;

upstream raw materials:

quinoline-2,6-diol

6-hydroxy-2-chloroquinoline

C₁₃H₁₄ClNO₂

C₁₉H₃₀BNO₄

Downstream raw materials:

2-(4-ethylaminophenyl)-6-[[2-(tetrahydro-2H-pyran-2-yloxy)-3-tosyloxy]propoxy]quinoline

C₂₂H₂₄N₂O₃

C₃₈H₅₀N₂O₇SSi

C₂₇H₂₈N₂O₅S