3-Ethoxy-4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine

Base Information

Chemical Name:3-Ethoxy-4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine
CAS No.:95579-18-3
Molecular Formula:C₈H₁₂N₂O₂
Molecular Weight:168.195
Hs Code.:
ChEMBL ID:CHEMBL1177913
DSSTox Substance ID:DTXSID001222065
Nikkaji Number:J550.922J
Mol file:95579-18-3.mol

Synonyms:3-Ethoxy-4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine;95579-18-3;CHEMBL1177913;SCHEMBL10654776;DTXSID001222065

Suppliers and Price of 3-Ethoxy-4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-Ethoxy-4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine

Chemical Property:

PSA：47.29000
LogP:1.04780
XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:168.089877630
Heavy Atom Count:12
Complexity:154

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC1=NOC2=C1CNCC2

Technology Process of 3-Ethoxy-4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine

There total 3 articles about 3-Ethoxy-4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 95597-29-8
methyl 3-ethoxy-6,7-dihydroisoxazolo-[4,5-c]pyridine-5(4H)-carboxylate

: 95579-18-3
3-Ethoxy-4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine

Guidance literature:: With potassium hydroxide; In methanol; water; for 15h; Heating;
DOI:10.1021/jm00156a018

Reference yield:

: 53601-98-2
methyl 3-hydroxy-4,5,6,7-tetrahydroisoxazolo<4,5-c>pyridine-5-carboxylate

: 95579-18-3
3-Ethoxy-4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) K₂CO₃ / 1.) acetone, 50 deg C, 1 h, 2.) acetone, 50 deg C, 20 h

2: KOH / methanol; H₂O / 15 h / Heating

With potassium hydroxide; potassium carbonate; In methanol; water;
DOI:10.1021/jm00156a018