benzyl [4-(2-{[4-(azetidin-1-yl)piperidine-1-carbonyl]amino}pyridin-4-yloxy)-2-fluorophenyl]carbamate

Base Information

Chemical Name:benzyl [4-(2-{[4-(azetidin-1-yl)piperidine-1-carbonyl]amino}pyridin-4-yloxy)-2-fluorophenyl]carbamate
CAS No.:864246-05-9
Molecular Formula:C₂₈H₃₀FN₅O₄
Molecular Weight:519.576
Hs Code.:

Synonyms:benzyl [4-(2-{[4-(azetidin-1-yl)piperidine-1-carbonyl]amino}pyridin-4-yloxy)-2-fluorophenyl]carbamate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of benzyl [4-(2-{[4-(azetidin-1-yl)piperidine-1-carbonyl]amino}pyridin-4-yloxy)-2-fluorophenyl]carbamate

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Technology Process of benzyl [4-(2-{[4-(azetidin-1-yl)piperidine-1-carbonyl]amino}pyridin-4-yloxy)-2-fluorophenyl]carbamate

There total 1 articles about benzyl [4-(2-{[4-(azetidin-1-yl)piperidine-1-carbonyl]amino}pyridin-4-yloxy)-2-fluorophenyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 864246-02-6
4-(azetidin-1-yl)piperidine dihydrochloride

: C₂₆H₂₀FN₃O₅

: 864246-05-9
benzyl [4-(2-{[4-(azetidin-1-yl)piperidine-1-carbonyl]amino}pyridin-4-yloxy)-2-fluorophenyl]carbamate

Guidance literature:: With triethylamine; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 10.5h;

Reference yield:

: 864246-05-9
benzyl [4-(2-{[4-(azetidin-1-yl)piperidine-1-carbonyl]amino}pyridin-4-yloxy)-2-fluorophenyl]carbamate

: 864248-48-6
4-(azetidin-1-yl)piperidine-1-carboxylic acid [4-(4-amino-3-fluorophenoxy)pyridin-2-yl]amide

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In tetrahydrofuran; at 20 ℃; for 16h; Product distribution / selectivity;