4-[3-(2,5-dimethyl-4-isopropylcarbonyl-phenyl)propargyl-amino]benzamidine

Base Information

Chemical Name:4-[3-(2,5-dimethyl-4-isopropylcarbonyl-phenyl)propargyl-amino]benzamidine
CAS No.:276673-65-5
Molecular Formula:C₂₂H₂₅N₃O
Molecular Weight:347.46
Hs Code.:

Synonyms:4-[3-(2,5-dimethyl-4-isopropylcarbonyl-phenyl)propargyl-amino]benzamidine

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Chemical Property of 4-[3-(2,5-dimethyl-4-isopropylcarbonyl-phenyl)propargyl-amino]benzamidine

Chemical Property:

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Technology Process of 4-[3-(2,5-dimethyl-4-isopropylcarbonyl-phenyl)propargyl-amino]benzamidine

There total 7 articles about 4-[3-(2,5-dimethyl-4-isopropylcarbonyl-phenyl)propargyl-amino]benzamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

: 276673-64-4
N-tert-butoxycarbonyl-4-[3-(2,5-dimethyl-4-isopropylcarbonyl-phenyl)propargylamino]benzamidine

: 276673-65-5
4-[3-(2,5-dimethyl-4-isopropylcarbonyl-phenyl)propargyl-amino]benzamidine

Guidance literature:: With trifluoroacetic acid;

Reference yield:

: 276677-24-8
4-bromo-2,5-dimethyl-1-isopropylcarbonyl-benzene

: 276673-65-5
4-[3-(2,5-dimethyl-4-isopropylcarbonyl-phenyl)propargyl-amino]benzamidine

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / tetrakis(triphenylphosphine)palladium ⁽⁰⁾ / acetonitrile

2: trifluoroacetic acid

With triethylamine; trifluoroacetic acid; tetrakis(triphenylphosphine)palladium ⁽⁰⁾; In acetonitrile;

Reference yield:

: 276677-06-6
4-propargylamino-benzamidine

: 276673-65-5
4-[3-(2,5-dimethyl-4-isopropylcarbonyl-phenyl)propargyl-amino]benzamidine

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide / tetrahydrofuran

2: triethylamine / tetrakis(triphenylphosphine)palladium ⁽⁰⁾ / acetonitrile

3: trifluoroacetic acid

With sodium hydroxide; triethylamine; trifluoroacetic acid; tetrakis(triphenylphosphine)palladium ⁽⁰⁾; In tetrahydrofuran; acetonitrile;