methyl 4-O-benzyl-3-O-(benzyloxymethyl)-5-deoxy-2-C-methyl-2-O-methyl-L-ribonate

Base Information

• Chemical Name: methyl 4-O-benzyl-3-O-(benzyloxymethyl)-5-deoxy-2-C-methyl-2-O-methyl-L-ribonate
• CAS No.: 130050-98-5
• Molecular Formula: C₂₃H₃₀O₆
• Molecular Weight: 402.488

Synonyms:methyl 4-O-benzyl-3-O-(benzyloxymethyl)-5-deoxy-2-C-methyl-2-O-methyl-L-ribonate

Chemical Property of methyl 4-O-benzyl-3-O-(benzyloxymethyl)-5-deoxy-2-C-methyl-2-O-methyl-L-ribonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 4-O-benzyl-3-O-(benzyloxymethyl)-5-deoxy-2-C-methyl-2-O-methyl-L-ribonate

There total 6 articles about methyl 4-O-benzyl-3-O-(benzyloxymethyl)-5-deoxy-2-C-methyl-2-O-methyl-L-ribonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Benzyloxymethyl chloride (3587-60-8) + (S)-4-Benzyloxy-3-hydroxy-2-methoxy-2-methyl-pentanoic acid methyl ester (97562-15-7,97590-94-8,97590-95-9,97590-96-0) → (S)-4-Benzyloxy-3-benzyloxymethoxy-2-methoxy-2-methyl-pentanoic acid methyl ester (130050-98-5,130050-99-6,130051-00-2)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; for 16h; 0 deg C --> room temperature;

DOI:10.1016/0008-6215(90)84068-6

Reference yield:

methyl 2-methoxypropionate (17639-76-8,92935-45-0) → (S)-4-Benzyloxy-3-benzyloxymethoxy-2-methoxy-2-methyl-pentanoic acid methyl ester (130050-98-5,130050-99-6,130051-00-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) LDA / 1) THF, -78 deg C, 30 min, 2) 5 min

2: 100 percent / diisopropylethylamine / CH₂Cl₂ / 16 h / 0 deg C --> room temperature

With N-ethyl-N,N-diisopropylamine; lithium diisopropyl amide; In dichloromethane;

DOI:10.1016/0008-6215(90)84068-6

Reference yield:

methyl 2-methoxypropionate (17639-76-8,92935-45-0) → methyl 4-O-benzyl-3-O-(benzyloxymethyl)-5-deoxy-2-C-methyl-2-O-methyl-L-ribonate (130050-98-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) LDA / 1) THF, -78 deg C, 30 min, 2) 5 min

2: diisopropylethylamine / CH₂Cl₂ / 16 h / 0 deg C --> room temperature

With N-ethyl-N,N-diisopropylamine; lithium diisopropyl amide; In dichloromethane;

DOI:10.1016/0008-6215(90)84068-6

upstream raw materials:

Benzyloxymethyl chloride

(S)-4-Benzyloxy-3-hydroxy-2-methoxy-2-methyl-pentanoic acid methyl ester

methyl 2-methoxypropionate

(S)-2-(benzyloxy)propanal

Downstream raw materials:

5-O-benzyl-4-O-(benzyloxymethyl)-2,6-dideoxy-3-C-methyl-3-O-methyl-L-ribohexose

4-O-benzyl-3-O-(benzyloxymethyl)-5-deoxy-2-C-methyl-2-O-methyl-L-ribose

(3R,4S,5S)-5-benzyloxy-4-(benzyloxy)methoxy-3-methoxy-3-methyl-hex-1-ene

5-O-benzyl-4-O-(benzyloxymethyl)-2,6-dideoxy-3-C-methyl-3-O-methyl-L-ribohexitol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 130050-98-5 methyl 4-O-benzyl-3-O-(benzyloxymethyl)-5-deoxy-2-C-methyl-2-O-methyl-L-ribonate

Send

Send

Metric Ton KG G Pound L ML

Send

Send