[3-(Morpholinomethyl)phenyl]methanol

Base Information

Chemical Name:[3-(Morpholinomethyl)phenyl]methanol
CAS No.:91271-64-6
Molecular Formula:C12H17 N O2
Molecular Weight:207.272
Hs Code.:
DSSTox Substance ID:DTXSID80428142
Wikidata:Q82240929
Mol file:91271-64-6.mol

Synonyms:[3-(morpholinomethyl)phenyl]methanol;91271-64-6;[3-(morpholin-4-ylmethyl)phenyl]methanol;{3-[(morpholin-4-yl)methyl]phenyl}methanol;(3-(Morpholinomethyl)phenyl)methanol;SCHEMBL2249512;DTXSID80428142;MFCD07772831;AKOS000320964;MS-22334;CS-0362865;FT-0763438;J-502745

Suppliers and Price of [3-(Morpholinomethyl)phenyl]methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
[3-(MORPHOLINOMETHYL)PHENYL]METHANOL 95.00%
1G
$ 757.97

American Custom Chemicals Corporation
[3-(MORPHOLINOMETHYL)PHENYL]METHANOL 95.00%
250MG
$ 622.15

Advanced Chemicals Intermediatesced Chemicals Intermediates
(3-Morpholin-4-ylmethyl-phenyl)-methanol 95%+
500mg
$ 108.75

Acints
(3-Morpholin-4-ylmethyl-phenyl)-methanol 95%+
500mg
$ 108.75

Total 13 raw suppliers

Chemical Property of [3-(Morpholinomethyl)phenyl]methanol

Chemical Property:

Vapor Pressure:4.6E-05mmHg at 25°C
Refractive Index:1.569
Boiling Point:335.8°Cat760mmHg
PKA:14.36±0.10(Predicted)
Flash Point:156.9°C
PSA：32.70000
Density:1.147g/cm³
LogP:0.94900
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:207.125928785
Heavy Atom Count:15
Complexity:181

Purity/Quality:

99% ^*data from raw suppliers

[3-(MORPHOLINOMETHYL)PHENYL]METHANOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1CC2=CC(=CC=C2)CO

Technology Process of [3-(Morpholinomethyl)phenyl]methanol

There total 5 articles about [3-(Morpholinomethyl)phenyl]methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 190660-95-8
methyl 3-((morpholin-4-yl)methyl)benzoate

: 91271-64-6
(3-(morpholinomethyl)phenyl)methanol

Guidance literature:: methyl 3-((morpholin-4-yl)methyl)benzoate; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃;

With sodium hydroxide; water; In tetrahydrofuran;

Reference yield: 43.0%

: 110-91-8,99108-56-2
morpholine

: 626-18-6
1,3-dimethanol benzene

: 91271-64-6
(3-(morpholinomethyl)phenyl)methanol

Guidance literature:: With trimethylamine-N-oxide; tricarbonyl(η⁴-1,3-bis(trimethylsilyl)-4,5,6,7-tetrahydro-2H-inden-2-one)iron; In toluene; at 20 - 135 ℃; for 18h; Schlenk technique; Inert atmosphere; Molecular sieve; Sealed tube;
DOI:10.1021/acscatal.5b02160

Reference yield:

: 99-36-5
1-methoxycarbonyl-3-methylbenzene

: 91271-64-6
(3-(morpholinomethyl)phenyl)methanol

Guidance literature:: Multi-step reaction with 3 steps

1: N-Bromosuccinimide / dibenzoyl peroxide / tetrachloromethane / 5 h / 50 °C / Heating / reflux

2: triethylamine / ethanol / 0 - 20 °C

3: lithium aluminium tetrahydride / tetrahydrofuran / 0 °C

With N-Bromosuccinimide; lithium aluminium tetrahydride; triethylamine; dibenzoyl peroxide; In tetrahydrofuran; tetrachloromethane; ethanol;