2,2-Dimethyl-propionic acid (2R,3S,4R,5R,6R)-3,4-bis-benzyloxy-6-[(1R,4S,5R,6R)-10-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-6-(4-methoxy-benzyloxy)-5-methyl-2-methylene-1-triethylsilanyloxy-decyl]-5-methyl-tetrahydro-pyran-2-ylmethyl ester

Base Information

Chemical Name:2,2-Dimethyl-propionic acid (2R,3S,4R,5R,6R)-3,4-bis-benzyloxy-6-[(1R,4S,5R,6R)-10-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-6-(4-methoxy-benzyloxy)-5-methyl-2-methylene-1-triethylsilanyloxy-decyl]-5-methyl-tetrahydro-pyran-2-ylmethyl ester
CAS No.:627537-35-3
Molecular Formula:C₆₈H₉₆O₁₀Si₂
Molecular Weight:1129.68
Hs Code.:

2,2-Dimethyl-propionic acid (2R,3S,4R,5R,6R)-3,4-bis-benzyloxy-6-[(1R,4S,5R,6R)-10-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-6-(4-methoxy-benzyloxy)-5-methyl-2-methylene-1-triethylsilanyloxy-decyl]-5-methyl-tetrahydro-pyran-2-ylmethyl ester

Synonyms:2,2-Dimethyl-propionic acid (2R,3S,4R,5R,6R)-3,4-bis-benzyloxy-6-[(1R,4S,5R,6R)-10-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-6-(4-methoxy-benzyloxy)-5-methyl-2-methylene-1-triethylsilanyloxy-decyl]-5-methyl-tetrahydro-pyran-2-ylmethyl ester

Suppliers and Price of 2,2-Dimethyl-propionic acid (2R,3S,4R,5R,6R)-3,4-bis-benzyloxy-6-[(1R,4S,5R,6R)-10-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-6-(4-methoxy-benzyloxy)-5-methyl-2-methylene-1-triethylsilanyloxy-decyl]-5-methyl-tetrahydro-pyran-2-ylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,2-Dimethyl-propionic acid (2R,3S,4R,5R,6R)-3,4-bis-benzyloxy-6-[(1R,4S,5R,6R)-10-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-6-(4-methoxy-benzyloxy)-5-methyl-2-methylene-1-triethylsilanyloxy-decyl]-5-methyl-tetrahydro-pyran-2-ylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2,2-Dimethyl-propionic acid (2R,3S,4R,5R,6R)-3,4-bis-benzyloxy-6-[(1R,4S,5R,6R)-10-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-6-(4-methoxy-benzyloxy)-5-methyl-2-methylene-1-triethylsilanyloxy-decyl]-5-methyl-tetrahydro-pyran-2-ylmethyl ester

There total 3 articles about 2,2-Dimethyl-propionic acid (2R,3S,4R,5R,6R)-3,4-bis-benzyloxy-6-[(1R,4S,5R,6R)-10-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-6-(4-methoxy-benzyloxy)-5-methyl-2-methylene-1-triethylsilanyloxy-decyl]-5-methyl-tetrahydro-pyran-2-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 79271-56-0
triethylsilyl trifluoromethyl sulfonate

: 627537-17-1
2,2-Dimethyl-propionic acid (2R,3S,4R,5R,6R)-3,4-bis-benzyloxy-6-[(1R,4S,5R,6R)-10-(tert-butyl-diphenyl-silanyloxy)-1,4-dihydroxy-6-(4-methoxy-benzyloxy)-5-methyl-2-methylene-decyl]-5-methyl-tetrahydro-pyran-2-ylmethyl ester

: 627537-35-3
2,2-Dimethyl-propionic acid (2R,3S,4R,5R,6R)-3,4-bis-benzyloxy-6-[(1R,4S,5R,6R)-10-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-6-(4-methoxy-benzyloxy)-5-methyl-2-methylene-1-triethylsilanyloxy-decyl]-5-methyl-tetrahydro-pyran-2-ylmethyl ester

Guidance literature:: With 2,6-dimethylpyridine; In dichloromethane; at -78 - 0 ℃;
DOI:10.1016/j.tetlet.2003.08.083

Reference yield:

: 365441-19-6
(1R,4S,5S,6R)-1-[(2R,3R,4R,5S,6R)-4,5-Bis-benzyloxy-6-(tert-butyl-dimethyl-silanyloxymethyl)-3-methyl-tetrahydro-pyran-2-yl]-4-(tert-butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-5-methyl-2-methylene-10-trityloxy-decan-1-ol

: 627537-35-3
2,2-Dimethyl-propionic acid (2R,3S,4R,5R,6R)-3,4-bis-benzyloxy-6-[(1R,4S,5R,6R)-10-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-6-(4-methoxy-benzyloxy)-5-methyl-2-methylene-1-triethylsilanyloxy-decyl]-5-methyl-tetrahydro-pyran-2-ylmethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 98 percent / TBAF / tetrahydrofuran / 60 °C

2: 96 percent / DMAP / CH₂Cl₂ / 0 °C

3: 81 percent / HCO₂H / diethyl ether / 0 °C

4: 100 percent / imidazole / CH₂Cl₂ / 20 °C

5: 72 percent / 2,6-lutidine / CH₂Cl₂ / -78 - 0 °C

With 1H-imidazole; 2,6-dimethylpyridine; dmap; formic acid; tetrabutyl ammonium fluoride; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1016/j.tetlet.2003.08.083

Reference yield:

: 627537-34-2
2,2-Dimethyl-propionic acid (2R,3S,4R,5R,6R)-3,4-bis-benzyloxy-5-methyl-6-[(1R,4S,5R,6R)-1,4,10-trihydroxy-6-(4-methoxy-benzyloxy)-5-methyl-2-methylene-decyl]-tetrahydro-pyran-2-ylmethyl ester

: 627537-35-3
2,2-Dimethyl-propionic acid (2R,3S,4R,5R,6R)-3,4-bis-benzyloxy-6-[(1R,4S,5R,6R)-10-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-6-(4-methoxy-benzyloxy)-5-methyl-2-methylene-1-triethylsilanyloxy-decyl]-5-methyl-tetrahydro-pyran-2-ylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / imidazole / CH₂Cl₂ / 20 °C

2: 72 percent / 2,6-lutidine / CH₂Cl₂ / -78 - 0 °C

With 1H-imidazole; 2,6-dimethylpyridine; In dichloromethane;
DOI:10.1016/j.tetlet.2003.08.083