Technology Process of C19H16BF2N3O2
There total 6 articles about C19H16BF2N3O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
N,N-dimethyl-formamide;
With
trichlorophosphate;
at 20 ℃;
Cooling with ice;
Inert atmosphere;
4,4-difluoro-8-(4-N,N0-dimethylaminophenyl)-4-bora-3a,4a-s-diaza-s-indacene;
In
1,2-dichloro-ethane;
at 80 ℃;
for 10h;
Inert atmosphere;
With
potassium carbonate;
In
water; 1,2-dichloro-ethane;
at 20 ℃;
regioselective reaction;
Inert atmosphere;
Cooling with ice;
DOI:10.1002/ejoc.201100736
- Guidance literature:
-
N,N-dimethyl-formamide;
With
trichlorophosphate;
at 20 ℃;
Cooling with ice;
Inert atmosphere;
C18H16BF2N3O;
In
1,2-dichloro-ethane;
at 80 ℃;
for 10h;
Inert atmosphere;
With
potassium carbonate;
In
water; 1,2-dichloro-ethane;
at 20 ℃;
regioselective reaction;
Inert atmosphere;
Cooling with ice;
DOI:10.1002/ejoc.201100736
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 0.17 h / Cooling with ice
2.1: boron trifluoride diethyl etherate; triethylamine / dichloromethane / 2 h / 20 °C
3.1: trichlorophosphate / 20 °C / Cooling with ice; Inert atmosphere
3.2: 10 h / 60 °C / Inert atmosphere
3.3: 20 °C / Inert atmosphere; Cooling with ice
4.1: trichlorophosphate / 20 °C / Cooling with ice; Inert atmosphere
4.2: 10 h / 80 °C / Inert atmosphere
4.3: 20 °C / Inert atmosphere; Cooling with ice
With
boron trifluoride diethyl etherate; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; trichlorophosphate;
In
dichloromethane;
3.1: Vilsmeier-Haack reaction / 3.2: Vilsmeier-Haack reaction / 3.3: Vilsmeier-Haack reaction / 4.1: Vilsmeier-Haack reaction / 4.2: Vilsmeier-Haack reaction / 4.3: Vilsmeier-Haack reaction;
DOI:10.1002/ejoc.201100736
