(+/-)-cis-[2-(prop-2-en-1-yl)]-cyclopentyl p-toluenesulfonate

Base Information

• Chemical Name: (+/-)-cis-[2-(prop-2-en-1-yl)]-cyclopentyl p-toluenesulfonate
• CAS No.: 130894-78-9
• Molecular Formula: C₁₅H₂₀O₃S
• Molecular Weight: 280.388
• Mol file: 130894-78-9.mol

Synonyms:(+/-)-cis-[2-(prop-2-en-1-yl)]-cyclopentyl p-toluenesulfonate

Chemical Property of (+/-)-cis-[2-(prop-2-en-1-yl)]-cyclopentyl p-toluenesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-cis-[2-(prop-2-en-1-yl)]-cyclopentyl p-toluenesulfonate

There total 3 articles about (+/-)-cis-[2-(prop-2-en-1-yl)]-cyclopentyl p-toluenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

(+/-)-cis-2-(prop-2-en-1-yl)-cyclopentanol (34686-64-1,54993-25-8,54993-26-9,55029-55-5,74743-88-7,74743-89-8,145166-23-0) + toluene-4-sulfonic acid (104-15-4) → (+/-)-cis-[2-(prop-2-en-1-yl)]-cyclopentyl p-toluenesulfonate (130894-78-9)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; In dichloromethane; at 0 - 20 ℃; for 2.08333h;

DOI:10.1039/c4ob01266f

Reference yield:

(+/-)-trans-2-(prop-2-en-1-yl)-cyclopentanol (74743-89-8) → (+/-)-cis-[2-(prop-2-en-1-yl)]-cyclopentyl p-toluenesulfonate (130894-78-9)

Guidance literature:

Multi-step reaction with 3 steps

1: triphenylphosphine; diethylazodicarboxylate / benzene / 4 h / 21 °C

2: potassium hydroxide / methanol; tetrahydrofuran / 1.5 h / 22 °C

3: 1,4-diaza-bicyclo[2.2.2]octane / dichloromethane / 2.08 h / 0 - 20 °C

With 1,4-diaza-bicyclo[2.2.2]octane; triphenylphosphine; potassium hydroxide; diethylazodicarboxylate; In tetrahydrofuran; methanol; dichloromethane; benzene;

DOI:10.1039/c4ob01266f

Reference yield:

cis-2-(prop-2-en-1-yl)cyclopent-1-yl 4-nitrobenzoate → (+/-)-cis-[2-(prop-2-en-1-yl)]-cyclopentyl p-toluenesulfonate (130894-78-9)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium hydroxide / methanol; tetrahydrofuran / 1.5 h / 22 °C

2: 1,4-diaza-bicyclo[2.2.2]octane / dichloromethane / 2.08 h / 0 - 20 °C

With 1,4-diaza-bicyclo[2.2.2]octane; potassium hydroxide; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1039/c4ob01266f

upstream raw materials:

(+/-)-trans-2-(prop-2-en-1-yl)-cyclopentanol

(+/-)-cis-2-(prop-2-en-1-yl)-cyclopentanol

toluene-4-sulfonic acid