Technology Process of 2,6-diketo-6-phenylhexanoic acid
There total 10 articles about 2,6-diketo-6-phenylhexanoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
NADPH;
HOPDA reducing enzyme III;
In
water;
at 25 ℃;
for 1h;
Yield given;
in potassium phosphate buffer at pH 7;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: silver carbonate / palladium diacetate / toluene / 80 °C
2: sodium hydroxide
With
sodium hydroxide; silver carbonate;
palladium diacetate;
In
toluene;
1: Heck reaction;
DOI:10.1039/b410322j
- Guidance literature:
-
Multi-step reaction with 9 steps
1: pyridinium p-toluenesulfonate / toluene / Heating
2: triethylamine / 1,2-dichloro-ethane / 2 h / Heating
3: silver carbonate / palladium diacetate / tetrahydrofuran
4: sulfuric acid; pyridinium p-toluenesulfonate / acetone / 1 h
5: sodium hydroxide / methanol / 2 h
6: Pseudomonas LB400 C-C hydrolase BphD / phosphate buffer / pH 8.0
7: tetrahydrofuran
8: silver carbonate / palladium diacetate / toluene / 80 °C
9: sodium hydroxide
With
sodium hydroxide; Pseudomonas LB400 C-C hydrolase BphD; sulfuric acid; pyridinium p-toluenesulfonate; triethylamine; silver carbonate;
palladium diacetate;
In
tetrahydrofuran; methanol; phosphate buffer; 1,2-dichloro-ethane; acetone; toluene;
3: Heck reaction / 8: Heck reaction;
DOI:10.1039/b410322j
