9-acetyl-cis-bicyclo<6.1.0>nonane tosylhydrazone

Base Information

• Chemical Name: 9-acetyl-cis-bicyclo<6.1.0>nonane tosylhydrazone
• CAS No.: 77745-96-1
• Molecular Formula: C₁₈H₂₆N₂O₂S
• Molecular Weight: 334.483
• Mol file: 77745-96-1.mol

Synonyms:9-acetyl-cis-bicyclo<6.1.0>nonane tosylhydrazone

Chemical Property of 9-acetyl-cis-bicyclo<6.1.0>nonane tosylhydrazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9-acetyl-cis-bicyclo<6.1.0>nonane tosylhydrazone

There total 4 articles about 9-acetyl-cis-bicyclo<6.1.0>nonane tosylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

9-acetyl-cis-bicyclo<6.1.0>nonane (34782-30-4,34782-31-5,77841-64-6) + toluene-4-sulfonic acid hydrazide (1576-35-8) → 9-acetyl-cis-bicyclo<6.1.0>nonane tosylhydrazone (77745-96-1)

Guidance literature:

In ethanol; 1.) 0 deg C, 45 min, 2.) room temperature, 1-2 h, 3.) 0 deg C, overnight;

DOI:10.1021/ja00399a025

Reference yield:

cis-Cyclooctene (931-88-4,931-87-3,25267-51-0) → 9-acetyl-cis-bicyclo<6.1.0>nonane tosylhydrazone (77745-96-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 60 percent / CuSO₄ / 3 h / 100 °C

2: 96 percent / NaOH, H₂O / 10 h / 80 °C

3: 97 percent / diethyl ether / 1.) 0 deg C, 1.5 h, 2.) reflux, 2.5 h

4: 90 percent / aq. ethanol / 1.) 0 deg C, 45 min, 2.) room temperature, 1-2 h, 3.) 0 deg C, overnight

With sodium hydroxide; water; copper(II) sulfate; In diethyl ether; ethanol;

DOI:10.1021/ja00399a025

Reference yield:

bicyclo<6.1.0>-9-ethyl ester (53235-18-0,53276-22-5,71117-27-6,72258-12-9) → 9-acetyl-cis-bicyclo<6.1.0>nonane tosylhydrazone (77745-96-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 96 percent / NaOH, H₂O / 10 h / 80 °C

2: 97 percent / diethyl ether / 1.) 0 deg C, 1.5 h, 2.) reflux, 2.5 h

3: 90 percent / aq. ethanol / 1.) 0 deg C, 45 min, 2.) room temperature, 1-2 h, 3.) 0 deg C, overnight

With sodium hydroxide; water; In diethyl ether; ethanol;

DOI:10.1021/ja00399a025

upstream raw materials:

9-acetyl-cis-bicyclo<6.1.0>nonane

toluene-4-sulfonic acid hydrazide

cis-Cyclooctene

cis-bicyclo<6.1.0>nonane-9-carboxylic acid

Downstream raw materials:

cis-Cyclooctene

9-methyl-cis-bicyclo<6.2.0>dec-9ene