(S)-N-tert-butoxycarbonyl-1-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-phenylethanamine

Base Information

• Chemical Name: (S)-N-tert-butoxycarbonyl-1-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-phenylethanamine
• CAS No.: 1202649-49-7
• Molecular Formula: C₁₈H₂₇NO₄
• Molecular Weight: 321.417
• Mol file: 1202649-49-7.mol

Synonyms:(S)-N-tert-butoxycarbonyl-1-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-phenylethanamine

Chemical Property of (S)-N-tert-butoxycarbonyl-1-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-phenylethanamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-N-tert-butoxycarbonyl-1-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-phenylethanamine

There total 1 articles about (S)-N-tert-butoxycarbonyl-1-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-phenylethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

(S)-N-benzyl-N-tert-butoxycarbonyl-1-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-phenylethanamine (1202649-48-6) → (S)-N-tert-butoxycarbonyl-1-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-phenylethanamine (1202649-49-7)

Guidance literature:

(S)-N-benzyl-N-tert-butoxycarbonyl-1-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-phenylethanamine; With ammonia; lithium; In diethyl ether; at -50 ℃;

With ammonium chloride; In diethyl ether; water;

DOI:10.1016/j.tetasy.2009.08.001

Reference yield: 90.0%

(S)-N-tert-butoxycarbonyl-1-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-phenylethanamine (1202649-49-7) → (2S,3S)-3-(t-butoxycarbonylamino)-4-phenylbutane-1,2-diol (149451-80-9)

Guidance literature:

With trifluoroacetic acid; In methanol; water; at 20 ℃; for 48h;

DOI:10.1016/j.tetasy.2009.08.001

upstream raw materials:

(S)-N-benzyl-N-tert-butoxycarbonyl-1-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-phenylethanamine

Downstream raw materials:

(2S,3S)-3-(t-butoxycarbonylamino)-4-phenylbutane-1,2-diol