3-Ethoxy-5-methoxythiophene-2-carboxylic acid

Base Information

Chemical Name:3-Ethoxy-5-methoxythiophene-2-carboxylic acid
CAS No.:95202-11-2
Molecular Formula:C₈H₁₀O₄S
Molecular Weight:202.231
Hs Code.:
DSSTox Substance ID:DTXSID60538975
Mol file:95202-11-2.mol

Synonyms:95202-11-2;3-Ethoxy-5-methoxythiophene-2-carboxylic acid;2-thiophenecarboxylic acid,3-ethoxy-5-methoxy-;DTXSID60538975

Suppliers and Price of 3-Ethoxy-5-methoxythiophene-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 3-Ethoxy-5-methoxythiophene-2-carboxylic acid

Chemical Property:

PSA：84.00000
LogP:1.85360
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:202.02997997
Heavy Atom Count:13
Complexity:185

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=C(SC(=C1)OC)C(=O)O

Technology Process of 3-Ethoxy-5-methoxythiophene-2-carboxylic acid

There total 4 articles about 3-Ethoxy-5-methoxythiophene-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5118-06-9
methyl 3-hydroxy-2-thiophenecarboxylate

: 95202-11-2
3-Ethoxy-5-methoxy-thiophene-2-carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 68 percent / sulphuryl chloride / CHCl₃ / 4 h / Ambient temperature

2: 10 h / Ambient temperature

3: K₂CO₃ / acetone / 5 h / Heating

4: 1M NaOH / 0.5 h / Heating

With sodium hydroxide; sulfuryl dichloride; potassium carbonate; In chloroform; acetone;

Reference yield:

: 19813-55-9
3-Hydroxy-5-methoxy-2-methoxycarbonylthiophene

: 95202-11-2
3-Ethoxy-5-methoxy-thiophene-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / acetone / 5 h / Heating

2: 1M NaOH / 0.5 h / Heating

With sodium hydroxide; potassium carbonate; In acetone;

Reference yield:

: 95201-94-8
methyl 2-chloro-3-oxo-2,3-dihydrothiophen-2-yl-carboxylate

: 95202-11-2
3-Ethoxy-5-methoxy-thiophene-2-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 10 h / Ambient temperature

2: K₂CO₃ / acetone / 5 h / Heating

3: 1M NaOH / 0.5 h / Heating

With sodium hydroxide; potassium carbonate; In acetone;