4-methyl-N,N-bis(5-(triethylsilyl)penta-2,4-diyn-1-yl)benzenesulfonamide

Base Information

• Chemical Name: 4-methyl-N,N-bis(5-(triethylsilyl)penta-2,4-diyn-1-yl)benzenesulfonamide
• CAS No.: 1507381-09-0
• Molecular Formula: C₂₉H₄₁NO₂SSi₂
• Molecular Weight: 523.887
• Mol file: 1507381-09-0.mol

Synonyms:4-methyl-N,N-bis(5-(triethylsilyl)penta-2,4-diyn-1-yl)benzenesulfonamide

Chemical Property of 4-methyl-N,N-bis(5-(triethylsilyl)penta-2,4-diyn-1-yl)benzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-methyl-N,N-bis(5-(triethylsilyl)penta-2,4-diyn-1-yl)benzenesulfonamide

There total 3 articles about 4-methyl-N,N-bis(5-(triethylsilyl)penta-2,4-diyn-1-yl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methyl-N,N-diprop-2-ynylbenzenesulfonamide (18773-54-1) + 1-bromo-2-triethylsilylacetylene (38177-63-8) → 4-methyl-N,N-bis(5-(triethylsilyl)penta-2,4-diyn-1-yl)benzenesulfonamide (1507381-09-0)

Guidance literature:

With hydroxylamine hydrochloride; N-butylamine; copper(l) chloride; In water;

DOI:10.1021/ol403237z

Reference yield:

2-triethylsilylacetylene (1777-03-3) + N,N-bis(3-bromoprop-2-yn-1-yl)-4-methylbenzenesulfonamide (1344089-60-6) → 4-methyl-N,N-bis(5-(triethylsilyl)penta-2,4-diyn-1-yl)benzenesulfonamide (1507381-09-0)

Guidance literature:

With hydroxylamine hydrochloride; N-butylamine; copper(l) chloride; In dichloromethane; at 0 - 20 ℃; for 0.0833333h; Inert atmosphere;

DOI:10.1021/acs.orglett.7b02438

Reference yield:

4-methyl-N,N-diprop-2-ynylbenzenesulfonamide (18773-54-1) → 4-methyl-N,N-bis(5-(triethylsilyl)penta-2,4-diyn-1-yl)benzenesulfonamide (1507381-09-0)

Guidance literature:

Multi-step reaction with 2 steps

1: N-Bromosuccinimide; silver nitrate / acetone / -78 - 20 °C / Inert atmosphere

2: copper(l) chloride; N-butylamine; hydroxylamine hydrochloride / dichloromethane / 0.08 h / 0 - 20 °C / Inert atmosphere

With N-Bromosuccinimide; hydroxylamine hydrochloride; silver nitrate; N-butylamine; copper(l) chloride; In dichloromethane; acetone;

DOI:10.1021/acs.orglett.7b02438

upstream raw materials:

4-methyl-N,N-diprop-2-ynylbenzenesulfonamide

1-bromo-2-triethylsilylacetylene

2-triethylsilylacetylene

N,N-bis(3-bromoprop-2-yn-1-yl)-4-methylbenzenesulfonamide

Downstream raw materials:

C₃₁H₄₅NO₄SSi₂

C₃₂H₄₃NO₄SSi₂

C₃₀H₄₅NO₃SSi₂

C₃₂H₄₉NO₃SSi₂