Technology Process of N-tosyl-2,3,4,12b-tetrahydro-7,10,11-trimethoxy-1H-<1>benzopyrane<4,3,2-ef><3>benzazepine
There total 7 articles about N-tosyl-2,3,4,12b-tetrahydro-7,10,11-trimethoxy-1H-<1>benzopyrane<4,3,2-ef><3>benzazepine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
chloroform;
for 12h;
under 760 Torr;
DOI:10.1016/0040-4020(96)00163-9
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 98 percent / NaBH4 / methanol
2: 38 percent / aq. H2SO4 / dioxane / 12 h / 110 °C
3: 59 percent / OsO4, NMMO monohydrate / H2O; tetrahydrofuran / Ambient temperature
4: 100 percent / conc. H2SO4, gl. AcOH / 0.05 h / Ambient temperature
5: 98 percent / NaBH4 / methanol
6: 53 percent / triphenylphosphine, diethyl azodicarboxylate / tetrahydrofuran / 3 h / Ambient temperature
7: 70 percent / aq. HCl, AcOH / 2 h / 75 °C
8: 96 percent / H2 / 10percent Pd/C / CHCl3 / 12 h / 760 Torr
With
hydrogenchloride; sodium tetrahydroborate; osmium(VIII) oxide; sulfuric acid; hydrogen; acetic acid; 4-methylmorpholine N-oxide; triphenylphosphine; diethylazodicarboxylate;
palladium on activated charcoal;
In
tetrahydrofuran; 1,4-dioxane; methanol; chloroform; water;
DOI:10.1016/0040-4020(96)00163-9
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 38 percent / aq. H2SO4 / dioxane / 12 h / 110 °C
2: 59 percent / OsO4, NMMO monohydrate / H2O; tetrahydrofuran / Ambient temperature
3: 100 percent / conc. H2SO4, gl. AcOH / 0.05 h / Ambient temperature
4: 98 percent / NaBH4 / methanol
5: 53 percent / triphenylphosphine, diethyl azodicarboxylate / tetrahydrofuran / 3 h / Ambient temperature
6: 70 percent / aq. HCl, AcOH / 2 h / 75 °C
7: 96 percent / H2 / 10percent Pd/C / CHCl3 / 12 h / 760 Torr
With
hydrogenchloride; sodium tetrahydroborate; osmium(VIII) oxide; sulfuric acid; hydrogen; acetic acid; 4-methylmorpholine N-oxide; triphenylphosphine; diethylazodicarboxylate;
palladium on activated charcoal;
In
tetrahydrofuran; 1,4-dioxane; methanol; chloroform; water;
DOI:10.1016/0040-4020(96)00163-9
