Technology Process of 2α-(benzyloxy)-7β-<1,1-(ethylenedioxy)ethyl>-4aβ-methyl-2,3,4,4a,5,6,7,8-octahydronaphthalene
There total 6 articles about 2α-(benzyloxy)-7β-<1,1-(ethylenedioxy)ethyl>-4aβ-methyl-2,3,4,4a,5,6,7,8-octahydronaphthalene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran;
for 17h;
Ambient temperature;
DOI:10.1021/jo00202a019
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 79 percent / p-toluenesulfonic acid, 4A molecular sieves / benzene / 4.5 h / Heating
2: LiAl(t-BuO)3H / benzene; tetrahydrofuran / 4 h / Heating
3: 98 percent / triphenylphosphine, diethyl azodicarboxylate / tetrahydrofuran / 17 h / Ambient temperature
With
4 A molecular sieve; toluene-4-sulfonic acid; lithium tri-t-butoxyaluminum hydride; triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran; benzene;
DOI:10.1021/jo00202a019
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 87 percent / concd. HCl / acetic acid / 26 h / 16 - 19 °C
2: 79 percent / p-toluenesulfonic acid, 4A molecular sieves / benzene / 4.5 h / Heating
3: LiAl(t-BuO)3H / benzene; tetrahydrofuran / 4 h / Heating
4: 98 percent / triphenylphosphine, diethyl azodicarboxylate / tetrahydrofuran / 17 h / Ambient temperature
With
hydrogenchloride; 4 A molecular sieve; toluene-4-sulfonic acid; lithium tri-t-butoxyaluminum hydride; triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran; acetic acid; benzene;
DOI:10.1021/jo00202a019
