N-trityl-(S)-2-aminopropanamide

Base Information

• Chemical Name: N-trityl-(S)-2-aminopropanamide
• CAS No.: 1418645-73-4
• Molecular Formula: C₂₂H₂₂N₂O
• Molecular Weight: 330.429
• Mol file: 1418645-73-4.mol

Synonyms:N-trityl-(S)-2-aminopropanamide

Chemical Property of N-trityl-(S)-2-aminopropanamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-trityl-(S)-2-aminopropanamide

There total 1 articles about N-trityl-(S)-2-aminopropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

triphenylmethyl alcohol (76-84-6) + (S)-alaninamide hydrochloride (33208-99-0) → N-trityl-(S)-2-aminopropanamide (1418645-73-4)

Guidance literature:

(S)-alaninamide hydrochloride; With sodium hydroxide; In water;

triphenylmethyl alcohol; With sulfuric acid; acetic anhydride; acetic acid; at 60 ℃; for 24h;

With sodium hydroxide; In water; ethyl acetate; pH=12;

DOI:10.1016/j.tetlet.2012.12.029

Reference yield: 99.0%

N-trityl-(S)-2-aminopropanamide (1418645-73-4) + trityl chloride (76-83-5) → N,N'-ditrityl-(S)-2-aminopropanamide (1418645-36-9)

Guidance literature:

With triethylamine; In chloroform; at 20 ℃; for 18h;

DOI:10.1016/j.tetlet.2012.12.029

Reference yield:

N-trityl-(S)-2-aminopropanamide (1418645-73-4) → C41H36N2O*C8H9NO (1418645-51-8)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / chloroform / 18 h / 20 °C

2: ethanol

With triethylamine; In ethanol; chloroform;

DOI:10.1016/j.tetlet.2012.12.029

upstream raw materials:

triphenylmethyl alcohol

(S)-alaninamide hydrochloride

Downstream raw materials:

C₄₁H₃₆N₂O*C₈H₉NO

C₄₁H₃₆N₂O*C₈H₉NO

C₄₁H₃₆N₂O*C₁₁H₁₅NO

C₄₁H₃₆N₂O*C₁₀H₁₂BrNO