1-Piperidinecarboxylicacid,5-amino-2,3,4-trihydroxy-,methylester,(2alpha,3beta,4beta,5alpha)-(9CI)

Base Information

Chemical Name:1-Piperidinecarboxylicacid,5-amino-2,3,4-trihydroxy-,methylester,(2alpha,3beta,4beta,5alpha)-(9CI)
CAS No.:94936-35-3
Molecular Formula:C₇H₁₄N₂O₅
Molecular Weight:206.199
Hs Code.:
Mol file:94936-35-3.mol

Synonyms:1-Piperidinecarboxylicacid, 5-amino-2,3,4-trihydroxy-, methyl ester, (2a,3b,4b,5a)- (9CI); 1-Piperidinecarboxylic acid,5-amino-2,3,4-trihydroxy-, methyl ester, (2a,3b,4b,5a)-(?à)-

Suppliers and Price of 1-Piperidinecarboxylicacid,5-amino-2,3,4-trihydroxy-,methylester,(2alpha,3beta,4beta,5alpha)-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 1-Piperidinecarboxylicacid,5-amino-2,3,4-trihydroxy-,methylester,(2alpha,3beta,4beta,5alpha)-(9CI)

Chemical Property:

PSA：116.25000
LogP:-1.92590

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-Piperidinecarboxylicacid,5-amino-2,3,4-trihydroxy-,methylester,(2alpha,3beta,4beta,5alpha)-(9CI)

There total 3 articles about 1-Piperidinecarboxylicacid,5-amino-2,3,4-trihydroxy-,methylester,(2alpha,3beta,4beta,5alpha)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 94936-26-2
methyl 2-benzyloxycarbonyl-7,8-dihydroxy-3-oxa-2,5-diazabicyclo<2.2.2>octane-5-carboxylate

: 94936-35-3
(2R,3S,4S,5R)-5-Amino-2,3,4-trihydroxy-piperidine-1-carboxylic acid methyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal;
DOI:10.1016/S0040-4039(01)81481-7

Reference yield:

: 94936-50-2,96212-80-5
(1S,4R)-3-Oxa-2,5-diaza-bicyclo[2.2.2]oct-7-ene-2,5-dicarboxylic acid 2-benzyl ester 5-methyl ester

: 94936-35-3
(2R,3S,4S,5R)-5-Amino-2,3,4-trihydroxy-piperidine-1-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: OsO₄, N-methylmorpholine-oxide / acetone; H₂O

2: H₂ / Pd/C

With osmium(VIII) oxide; hydrogen; 4-methylmorpholine N-oxide; palladium on activated charcoal; In water; acetone;
DOI:10.1016/S0040-4039(01)81481-7

Reference yield:

: 33707-36-7
1-(methoxycarbonyl)-1,2-dihydropyridine

: 94936-35-3
(2R,3S,4S,5R)-5-Amino-2,3,4-trihydroxy-piperidine-1-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Pr₄NIO₄; 2.) N-methylmorpholine N-oxide hydrate / 2.) OsO₄ + t-BuOOH/BuOH / 1.) 1h, 0 deg.C; 2.) 1 h, 0 deg.C, 3.) room temp.

2: H₂ / Pd/C / ethanol / 760 Torr / Ambient temperature

With tetrapropylammonium periodate; hydrogen; 4-methylmorpholine N-oxide; tert.-butylhydroperoxide; palladium on activated charcoal; osmium(VIII) oxide; butan-1-ol; In ethanol;
DOI:10.1002/hlca.19870700308