2''-(2-methoxy-ethyl)-5-phenyl-1H,3'H,3''H-[2,5';2',5'']terbenzoimidazole

Base Information

• Chemical Name: 2''-(2-methoxy-ethyl)-5-phenyl-1H,3'H,3''H-[2,5';2',5'']terbenzoimidazole
• CAS No.: 237429-51-5
• Molecular Formula: C₃₀H₂₄N₆O
• Molecular Weight: 484.56
• Mol file: 237429-51-5.mol

Synonyms:2''-(2-methoxy-ethyl)-5-phenyl-1H,3'H,3''H-[2,5';2',5'']terbenzoimidazole

Chemical Property of 2''-(2-methoxy-ethyl)-5-phenyl-1H,3'H,3''H-[2,5';2',5'']terbenzoimidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2''-(2-methoxy-ethyl)-5-phenyl-1H,3'H,3''H-[2,5';2',5'']terbenzoimidazole

There total 4 articles about 2''-(2-methoxy-ethyl)-5-phenyl-1H,3'H,3''H-[2,5';2',5'']terbenzoimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-(3,4-diaminophenyl)-5-phenyl-benzimidazole (237429-60-6) + 5-formyl-2-(2-methoxyethyl)benzimidazole (237429-69-5) → 2''-(2-methoxy-ethyl)-5-phenyl-1H,3'H,3''H-[2,5';2',5'']terbenzoimidazole (237429-51-5)

Guidance literature:

In nitrobenzene; at 145 ℃; for 15h;

DOI:10.1016/S0968-0896(00)00054-7

Reference yield:

4-cyano-1,2-phenylenediamine (17626-40-3) → 2''-(2-methoxy-ethyl)-5-phenyl-1H,3'H,3''H-[2,5';2',5'']terbenzoimidazole (237429-51-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 50 percent / aq. HCl / 7 h / Heating

2: 65 percent / aq. HCOOH / Ni-Al / 5.5 h / 95 °C

3: 80 percent / nitrobenzene / 15 h / 145 °C

With hydrogenchloride; formic acid; aluminum nickel; In nitrobenzene; 1: Condensation / 2: Reduction / 3: Condensation;

DOI:10.1016/S0968-0896(00)00054-7

Reference yield:

2-(3,4-dinitrophenyl)-5-phenylbenzimidazole (192879-70-2) → 2''-(2-methoxy-ethyl)-5-phenyl-1H,3'H,3''H-[2,5';2',5'']terbenzoimidazole (237429-51-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / H₂ / Pd/C / ethyl acetate / 1.5 h

2: 80 percent / nitrobenzene / 15 h / 145 °C

With hydrogen; palladium on activated charcoal; In ethyl acetate; nitrobenzene; 1: Hydrogenation / 2: Condensation;

DOI:10.1016/S0968-0896(00)00054-7

upstream raw materials:

2-(3,4-diaminophenyl)-5-phenyl-benzimidazole

5-formyl-2-(2-methoxyethyl)benzimidazole

4-cyano-1,2-phenylenediamine

2-(3,4-dinitrophenyl)-5-phenylbenzimidazole