Uridine, 2',3'-didehydro-2',3'-dideoxy-5'-O-[(1,1-dimethylethyl)diphenylsilyl]-5-methyl-2'-(phenylsulfonyl)-

Base Information

Chemical Name:Uridine, 2',3'-didehydro-2',3'-dideoxy-5'-O-[(1,1-dimethylethyl)diphenylsilyl]-5-methyl-2'-(phenylsulfonyl)-
CAS No.:171357-27-0
Molecular Formula:C₃₂H₃₄N₂O₆SSi
Molecular Weight:602.783
Hs Code.:
DSSTox Substance ID:DTXSID901109224

Synonyms:DTXSID901109224;171357-27-0

Suppliers and Price of Uridine, 2',3'-didehydro-2',3'-dideoxy-5'-O-[(1,1-dimethylethyl)diphenylsilyl]-5-methyl-2'-(phenylsulfonyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Uridine, 2',3'-didehydro-2',3'-dideoxy-5'-O-[(1,1-dimethylethyl)diphenylsilyl]-5-methyl-2'-(phenylsulfonyl)-

Chemical Property:

Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:602.19068452
Heavy Atom Count:42
Complexity:1150

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CN(C(=O)NC1=O)C2C(=CC(O2)CO[Si](C3=CC=CC=C3)(C4=CC=CC=C4)C(C)(C)C)S(=O)(=O)C5=CC=CC=C5
Isomeric SMILES:CC1=CN(C(=O)NC1=O)[C@H]2C(=C[C@H](O2)CO[Si](C3=CC=CC=C3)(C4=CC=CC=C4)C(C)(C)C)S(=O)(=O)C5=CC=CC=C5

Technology Process of Uridine, 2',3'-didehydro-2',3'-dideoxy-5'-O-[(1,1-dimethylethyl)diphenylsilyl]-5-methyl-2'-(phenylsulfonyl)-

There total 3 articles about Uridine, 2',3'-didehydro-2',3'-dideoxy-5'-O-[(1,1-dimethylethyl)diphenylsilyl]-5-methyl-2'-(phenylsulfonyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1-<5-(O-t-butyldiphenylsilyl)-2,3-dideoxy-2-phenylthio-D-glycero-pent-2-enofuranosyl>thymine

: 171357-27-0
1-<5-(O-t-butyldiphenylsilyl)-2,3-dideoxy-2-phenylsulfonyl-β-D-glycero-pent-2-enofuranosyl>thymine

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; for 1.5h; Ambient temperature;
DOI:10.1246/bcsj.68.2327

Reference yield:

: 1-[(S)-3-Benzenesulfinyl-5-(tert-butyl-diphenyl-silanyloxymethyl)-3-phenylsulfanyl-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione

: 171357-27-0
1-<5-(O-t-butyldiphenylsilyl)-2,3-dideoxy-2-phenylsulfonyl-β-D-glycero-pent-2-enofuranosyl>thymine

Guidance literature:: Multi-step reaction with 2 steps

1: tri-n-butylamine / xylene / 2 h / Heating

2: 97 percent / mCPBA / CH₂Cl₂ / 1.5 h / Ambient temperature

With tributyl-amine; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; xylene;
DOI:10.1246/bcsj.68.2327

Reference yield:

: 1-[(S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-3,3-bis-phenylsulfanyl-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione

: 171357-27-0
1-<5-(O-t-butyldiphenylsilyl)-2,3-dideoxy-2-phenylsulfonyl-β-D-glycero-pent-2-enofuranosyl>thymine

Guidance literature:: Multi-step reaction with 3 steps

1: mCPBA / CH₂Cl₂ / 0.17 h / 0 °C

2: tri-n-butylamine / xylene / 2 h / Heating

3: 97 percent / mCPBA / CH₂Cl₂ / 1.5 h / Ambient temperature

With tributyl-amine; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; xylene;
DOI:10.1246/bcsj.68.2327