6-ETHYL ISATIN

Base Information

• Chemical Name: 6-ETHYL ISATIN
• CAS No.: 90924-07-5
• Molecular Formula: C10H9 N O2
• Molecular Weight: 175.18
• Mol file: 90924-07-5.mol

Synonyms:Indole-2,3-dione,6-ethyl- (7CI); 6-Ethylindoline-2,3-dione; 6-Ethylisatin

Chemical Property of 6-ETHYL ISATIN

Chemical Property:

• PSA: 46.17000
• LogP: 1.52180

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-ETHYL ISATIN

There total 5 articles about 6-ETHYL ISATIN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

→ 6-ethyl-1H-indole-2,3-dione (90924-07-5)

Guidance literature:

With peracetic acid; copper(l) iodide; In ethanol; at 60 ℃; for 0.166667h; Microwave irradiation;

Reference yield: 34.0%

hydroxyimino-acetic acid-(3-ethyl-anilide) (34934-04-8) → 6-ethyl-1H-indole-2,3-dione (90924-07-5) + 4-Ethyl-1H-indole-2,3-dione (34934-05-9)

Guidance literature:

With sulfuric acid; water; at 50 - 80 ℃; for 0.166667h;

Reference yield:

m-ethylaniline (587-02-0) → 6-ethyl-1H-indole-2,3-dione (90924-07-5)

Guidance literature:

Multi-step reaction with 2 steps

1: NH₂OH+HCl; Na₂SO₄; water

2: aqueous sulfuric acid

With hydrogenchloride; sulfuric acid; water; hydroxylamine; sodium sulfate;

DOI:10.1021/jo01135a015

upstream raw materials:

hydroxyimino-acetic acid-(3-ethyl-anilide)

1-(3-aminophenyl)ethanone

m-ethylaniline

3-Nitroacetophenone

Downstream raw materials:

4-ethyl anthranilic acid

4-[N'-(6-Ethyl-2-oxo-1,2-dihydro-indol-3-ylidene)-hydrazino]-benzenesulfonamide

Refernces

• 1、 -. "QUINOLINE DERIVATIVES". Page/Page column 7. . Retrieved 2008/06/13.
• 2、 -. "4H-3,1-BENZOXAZIN-4-ONES AND RELATED COMPOUNDS AND USE AS ENZYME INHIBITORS". . . Retrieved 2008/06/13.