tert-Butyl 1-((benzyloxy)carbonyl)vinylcarbamate

Base Information

• Chemical Name: tert-Butyl 1-((benzyloxy)carbonyl)vinylcarbamate
• CAS No.: 94882-75-4
• Molecular Formula: C15H19 N O4
• Molecular Weight: 277.32
• Hs Code.: 2924299090
• DSSTox Substance ID: DTXSID60474187
• Nikkaji Number: J376.615B
• Wikidata: Q82304023
• Mol file: 94882-75-4.mol

Synonyms:N-Boc-dehydroAla-OBn;94882-75-4;tert-Butyl 1-((benzyloxy)carbonyl)vinylcarbamate;Benzyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]prop-2-enoate;benzyl 2-{[(tert-butoxy)carbonyl]amino}prop-2-enoate;Benzyl 2-((tert-butoxycarbonyl)amino)acrylate;SCHEMBL1196890;DTXSID60474187;GFIUMOFCXSETHX-UHFFFAOYSA-N;benzyl 2-(tert-butoxycarbonyl)acrylate;FT-0603897;A19345;2-tert-butoxycarbonylamino-acrylic acid benzyl ester;J-524383

Chemical Property of tert-Butyl 1-((benzyloxy)carbonyl)vinylcarbamate

Chemical Property:

• PSA: 68.12000
• LogP: 2.97260
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 277.13140809
• Heavy Atom Count: 20
• Complexity: 365

Purity/Quality:

97% ^*data from raw suppliers

BENZYL 2-(TERT-BUTOXYCARBONYLAMINO)ACRYLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)OC(=O)NC(=C)C(=O)OCC1=CC=CC=C1

Technology Process of tert-Butyl 1-((benzyloxy)carbonyl)vinylcarbamate

There total 20 articles about tert-Butyl 1-((benzyloxy)carbonyl)vinylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Boc-Ser(PO3Ph2)-OBzl (106815-62-7) → benzyl (2-t-butoxycarbonylamino)acrylate (94882-75-4)

Guidance literature:

With N-methylcyclohexylamine; In dichloromethane; for 1.5h; Ambient temperature;

DOI:10.1016/S0040-4039(00)98047-X

Reference yield: 100.0%

Boc-Ser(PO3Tc2)-OBzl (130834-98-9) → benzyl (2-t-butoxycarbonylamino)acrylate (94882-75-4)

Guidance literature:

With N-methylcyclohexylamine; In dichloromethane; for 1.5h; Ambient temperature;

DOI:10.1016/S0040-4039(00)98047-X

Reference yield: 91.0%

N-tert-butoxycarbonyl-L-serine benzyl ester (59524-02-6) → benzyl (2-t-butoxycarbonylamino)acrylate (94882-75-4)

Guidance literature:

With methyl 4-hydroxylbenzoate; triphenylphosphine; diethylazodicarboxylate; In benzene; for 15h; Ambient temperature;

DOI:10.1021/jo951958t

upstream raw materials:

2-t-butoxycarbonylamino-3-hydroxypropionic acid benzyl ester

Boc-Ser(PO₃Ph₂)-OBzl

Boc-Ser(PO₃Tc₂)-OBzl

benzyl 2(S)-(tert-butoxycarbonylamino)-3-p-toluenesulfonylpropionate

Downstream raw materials:

(Z)-2-tert-Butoxycarbonylamino-3-(4-nitro-phenyl)-acrylic acid benzyl ester

(Z)-2-tert-Butoxycarbonylamino-3-phenyl-acrylic acid benzyl ester

benzyl N-(tert-butoxycarbonyl)indole-2-carboxylate

1-{2-(benzyloxycarbonyl)-2-[(tert-butoxycarbonyl)amino]ethenyl}-3-bromobenzene