2,6-dimethylphenyl 2,3-diphenylpropanoate

Base Information

• Chemical Name: 2,6-dimethylphenyl 2,3-diphenylpropanoate
• CAS No.: 1427179-45-0
• Molecular Formula: C₂₃H₂₂O₂
• Molecular Weight: 330.426
• Mol file: 1427179-45-0.mol

Synonyms:2,6-dimethylphenyl 2,3-diphenylpropanoate

Chemical Property of 2,6-dimethylphenyl 2,3-diphenylpropanoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2,6-dimethylphenyl 2,3-diphenylpropanoate

There total 1 articles about 2,6-dimethylphenyl 2,3-diphenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2.6-dimethylphenol (576-26-1,25134-01-4) + 2,3-diphenylpropanoic acid (94942-89-9) → 2,6-dimethylphenyl 2,3-diphenylpropanoate (1427179-45-0)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 18h;

DOI:10.1021/ol400392r

Reference yield: 70.0%

n-butyllithium (109-72-8,29786-93-4) + trifluoromethylsulfonic anhydride (358-23-6) + 2,6-dimethylphenyl 2,3-diphenylpropanoate (1427179-45-0) → (Z)-1,2-diphenylhept-2-en-3-yl trifluoromethanesulfonate (1427179-60-9)

Guidance literature:

2,6-dimethylphenyl 2,3-diphenylpropanoate; With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 1h; Inert atmosphere;

n-butyllithium; In diethyl ether; hexane; at -78 - -20 ℃; Inert atmosphere;

trifluoromethylsulfonic anhydride; In diethyl ether; hexane; at -20 - 22 ℃; for 15h; diastereoselective reaction; Inert atmosphere;

DOI:10.1021/ol400392r

upstream raw materials:

2.6-dimethylphenol

2,3-diphenylpropanoic acid

Downstream raw materials:

(Z)-1,2-diphenylhept-2-en-3-yl trifluoromethanesulfonate