8-phthalimido-3,6-dioxaoctyl 2,3,6-tri-O-benzyl-4-O-(2,6-di-O-benzyl-3-O-methoxycarbonylmethylene-β-D-galactopyranosyl)-β-D-glucopyranoside

Base Information

Chemical Name:8-phthalimido-3,6-dioxaoctyl 2,3,6-tri-O-benzyl-4-O-(2,6-di-O-benzyl-3-O-methoxycarbonylmethylene-β-D-galactopyranosyl)-β-D-glucopyranoside
CAS No.:733051-88-2
Molecular Formula:C₆₄H₇₁NO₁₇
Molecular Weight:1126.26
Hs Code.:

Synonyms:8-phthalimido-3,6-dioxaoctyl 2,3,6-tri-O-benzyl-4-O-(2,6-di-O-benzyl-3-O-methoxycarbonylmethylene-β-D-galactopyranosyl)-β-D-glucopyranoside

Suppliers and Price of 8-phthalimido-3,6-dioxaoctyl 2,3,6-tri-O-benzyl-4-O-(2,6-di-O-benzyl-3-O-methoxycarbonylmethylene-β-D-galactopyranosyl)-β-D-glucopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 8-phthalimido-3,6-dioxaoctyl 2,3,6-tri-O-benzyl-4-O-(2,6-di-O-benzyl-3-O-methoxycarbonylmethylene-β-D-galactopyranosyl)-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 8-phthalimido-3,6-dioxaoctyl 2,3,6-tri-O-benzyl-4-O-(2,6-di-O-benzyl-3-O-methoxycarbonylmethylene-β-D-galactopyranosyl)-β-D-glucopyranoside

There total 6 articles about 8-phthalimido-3,6-dioxaoctyl 2,3,6-tri-O-benzyl-4-O-(2,6-di-O-benzyl-3-O-methoxycarbonylmethylene-β-D-galactopyranosyl)-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.7%

: 96-32-2
bromoacetic acid methyl ester

: 733051-87-1
8-phthalimido-3,6-dioxaoctyl 2,3,6-tri-O-benzyl-4-O-(2,6-di-O-benzyl-β-D-galactopyranosyl)-β-D-glucopyranoside

: 733051-88-2
8-phthalimido-3,6-dioxaoctyl 2,3,6-tri-O-benzyl-4-O-(2,6-di-O-benzyl-3-O-methoxycarbonylmethylene-β-D-galactopyranosyl)-β-D-glucopyranoside

Guidance literature:: 8-phthalimido-3,6-dioxaoctyl 2,3,6-tri-O-benzyl-4-O-(2,6-di-O-benzyl-β-D-galactopyranosyl)-β-D-glucopyranoside; With di(n-butyl)tin oxide; In toluene; for 4h; Heating;

bromoacetic acid methyl ester; With tetra-(n-butyl)ammonium iodide; In toluene; at 80 ℃; for 2.5h;

With sodium methylate; In methanol; at 20 ℃; for 2.5h;
DOI:10.1016/j.carres.2004.03.028

Reference yield:

: 85-44-9
phthalic anhydride

: 733051-88-2
8-phthalimido-3,6-dioxaoctyl 2,3,6-tri-O-benzyl-4-O-(2,6-di-O-benzyl-3-O-methoxycarbonylmethylene-β-D-galactopyranosyl)-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 6 steps

1.1: hydrogen / Pd/C / ethyl acetate; acetic acid / 6 h / 3150.25 Torr

1.2: Et₃N / methanol / 24 h / 20 °C

1.3: 79.9 percent / pyridine / 20 °C

2.1: 97.7 percent / NaOMe / methanol / 3 h / 20 °C

3.1: p-toluenesulfonic acid hydrate / dimethylformamide / 24 h / 20 °C

3.2: 84 percent / Et₃N / methanol; H₂O / 4 h / Heating

4.1: 28.8 percent / Ag₂O / dimethylformamide / 0.25 h / ultrasonic irradiation

5.1: 89.3 percent / CF₃COOH / H₂O; CH₂Cl₂ / 0.5 h

6.1: Bu₂SnO / toluene / 4 h / Heating

6.2: Bu₄NI / toluene / 2.5 h / 80 °C

6.3: 82.7 percent / NaOMe / methanol / 2.5 h / 20 °C

With hydrogen; sodium methylate; di(n-butyl)tin oxide; toluene-4-sulfonic acid; trifluoroacetic acid; silver(l) oxide; palladium on activated charcoal; In methanol; dichloromethane; water; acetic acid; ethyl acetate; N,N-dimethyl-formamide; toluene;
DOI:10.1016/j.carres.2004.03.028

Reference yield:

: 733051-90-6
2-[2-(2-{2-[(2R,3R,4R,5S,6R)-3,4-Dihydroxy-6-hydroxymethyl-5-((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-yloxy]-ethoxy}-ethoxy)-ethyl]-isoindole-1,3-dione

: 733051-88-2
8-phthalimido-3,6-dioxaoctyl 2,3,6-tri-O-benzyl-4-O-(2,6-di-O-benzyl-3-O-methoxycarbonylmethylene-β-D-galactopyranosyl)-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 4 steps

1.1: p-toluenesulfonic acid hydrate / dimethylformamide / 24 h / 20 °C

1.2: 84 percent / Et₃N / methanol; H₂O / 4 h / Heating

2.1: 28.8 percent / Ag₂O / dimethylformamide / 0.25 h / ultrasonic irradiation

3.1: 89.3 percent / CF₃COOH / H₂O; CH₂Cl₂ / 0.5 h

4.1: Bu₂SnO / toluene / 4 h / Heating

4.2: Bu₄NI / toluene / 2.5 h / 80 °C

4.3: 82.7 percent / NaOMe / methanol / 2.5 h / 20 °C

With di(n-butyl)tin oxide; toluene-4-sulfonic acid; trifluoroacetic acid; silver(l) oxide; In dichloromethane; water; N,N-dimethyl-formamide; toluene;
DOI:10.1016/j.carres.2004.03.028