(R)-(+)-3-hydroxymethyl-1-methyl-3-((p-toluenesulfonyloxy)methyl)oxindole

Base Information

Chemical Name:(R)-(+)-3-hydroxymethyl-1-methyl-3-((p-toluenesulfonyloxy)methyl)oxindole
CAS No.:1244784-39-1
Molecular Formula:C₁₈H₁₉NO₅S
Molecular Weight:361.419
Hs Code.:

Synonyms:(R)-(+)-3-hydroxymethyl-1-methyl-3-((p-toluenesulfonyloxy)methyl)oxindole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-(+)-3-hydroxymethyl-1-methyl-3-((p-toluenesulfonyloxy)methyl)oxindole

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Technology Process of (R)-(+)-3-hydroxymethyl-1-methyl-3-((p-toluenesulfonyloxy)methyl)oxindole

There total 1 articles about (R)-(+)-3-hydroxymethyl-1-methyl-3-((p-toluenesulfonyloxy)methyl)oxindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 98-59-9
p-toluenesulfonyl chloride

: 374898-38-1
3,3-bis(hydroxymethyl)-1-methyloxindole

: 1244784-39-1
(R)-(+)-3-hydroxymethyl-1-methyl-3-((p-toluenesulfonyloxy)methyl)oxindole

Guidance literature:: With copper(II) bis(trifluoromethanesulfonate); potassium carbonate; (4R,4'R)-2,2'-(propane-2,2'diyl)bis(4-phenyl-4,5-dihydrooxazole); at 20 ℃; for 24h; optical yield given as %ee; enantioselective reaction;
DOI:10.1016/j.tetasy.2010.03.015