N-[(E)-2-diethoxyphosphorylethylideneamino]-4-methyl-benzenesulfonamide

Base Information

• Chemical Name: N-[(E)-2-diethoxyphosphorylethylideneamino]-4-methyl-benzenesulfonamide
• CAS No.: 208511-62-0
• Molecular Formula: C₁₃H₂₁N₂O₅PS
• Molecular Weight: 348.36
• Mol file: 208511-62-0.mol

Synonyms:N-[(E)-2-diethoxyphosphorylethylideneamino]-4-methyl-benzenesulfonamide

Chemical Property of N-[(E)-2-diethoxyphosphorylethylideneamino]-4-methyl-benzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[(E)-2-diethoxyphosphorylethylideneamino]-4-methyl-benzenesulfonamide

There total 2 articles about N-[(E)-2-diethoxyphosphorylethylideneamino]-4-methyl-benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl phosphonoacetaldehyde diethyl acetal (7598-61-0) + toluene-4-sulfonic acid hydrazide (1576-35-8) → anti-diethoxyphosphorylacetaldehyde tosylhydrazone + N-[(E)-2-diethoxyphosphorylethylideneamino]-4-methyl-benzenesulfonamide (208511-62-0)

Guidance literature:

With hydrogenchloride; at 63 - 65 ℃; for 2h; Yield given. Yields of byproduct given;

DOI:10.1016/S0040-4039(98)00472-9

Reference yield:

anti-diethoxyphosphorylacetaldehyde tosylhydrazone → N-[(E)-2-diethoxyphosphorylethylideneamino]-4-methyl-benzenesulfonamide (208511-62-0)

Guidance literature:

In chloroform-d1; isomerization in CDCl₃ and on SiO₂;

DOI:10.1016/S0040-4039(98)00472-9

Reference yield: 80.0%

N-[(E)-2-diethoxyphosphorylethylideneamino]-4-methyl-benzenesulfonamide (208511-62-0) → Diethyl 1-formylethylphosphonate tosylhydrazone (222180-58-7)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; 1.) -70 deg C, 15 min, 2.) -78 deg C, 90 min;

DOI:10.1055/s-1999-2608

upstream raw materials:

diethyl phosphonoacetaldehyde diethyl acetal

toluene-4-sulfonic acid hydrazide