N-((3S)-N-(O-benzyl-N-Boc-L-aspartyl)-1,2,3,4-tetrahydroisoquinoline-3-carbonyl)-L-aspartic acid dibenzyl ester

Base Information

Chemical Name:N-((3S)-N-(O-benzyl-N-Boc-L-aspartyl)-1,2,3,4-tetrahydroisoquinoline-3-carbonyl)-L-aspartic acid dibenzyl ester
CAS No.:1219835-35-4
Molecular Formula:C₄₄H₄₇N₃O₁₀
Molecular Weight:777.871
Hs Code.:

Synonyms:N-((3S)-N-(O-benzyl-N-Boc-L-aspartyl)-1,2,3,4-tetrahydroisoquinoline-3-carbonyl)-L-aspartic acid dibenzyl ester

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Chemical Property of N-((3S)-N-(O-benzyl-N-Boc-L-aspartyl)-1,2,3,4-tetrahydroisoquinoline-3-carbonyl)-L-aspartic acid dibenzyl ester

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Technology Process of N-((3S)-N-(O-benzyl-N-Boc-L-aspartyl)-1,2,3,4-tetrahydroisoquinoline-3-carbonyl)-L-aspartic acid dibenzyl ester

There total 1 articles about N-((3S)-N-(O-benzyl-N-Boc-L-aspartyl)-1,2,3,4-tetrahydroisoquinoline-3-carbonyl)-L-aspartic acid dibenzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 2791-79-9
dibenzyl L-aspartate

: 1219835-19-4
(3S)-N-(O-benzyl-N-Boc-L-aspartyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

: 1219835-35-4
N-((3S)-N-(O-benzyl-N-Boc-L-aspartyl)-1,2,3,4-tetrahydroisoquinoline-3-carbonyl)-L-aspartic acid dibenzyl ester

Guidance literature:: With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran; at 0 - 20 ℃; for 14h; under 750.075 Torr; pH=9; Inert atmosphere;
DOI:10.1016/j.bmc.2010.01.009