(1-(2-Chloro-phenyl)-5-(4-chloro-phenyl)-3-{methyl-[(R)-1-(4-trifluoromethyl-phenyl)-ethyl]-carbamoyl}-1H-pyrazol-4-yl)-acetic acid ethyl ester

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Chemical Name:(1-(2-Chloro-phenyl)-5-(4-chloro-phenyl)-3-{methyl-[(R)-1-(4-trifluoromethyl-phenyl)-ethyl]-carbamoyl}-1H-pyrazol-4-yl)-acetic acid ethyl ester
CAS No.:1034265-92-3
Molecular Formula:C₃₀H₂₆Cl₂F₃N₃O₃
Molecular Weight:604.456
Hs Code.:

Synonyms:(1-(2-Chloro-phenyl)-5-(4-chloro-phenyl)-3-{methyl-[(R)-1-(4-trifluoromethyl-phenyl)-ethyl]-carbamoyl}-1H-pyrazol-4-yl)-acetic acid ethyl ester

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Chemical Property of (1-(2-Chloro-phenyl)-5-(4-chloro-phenyl)-3-{methyl-[(R)-1-(4-trifluoromethyl-phenyl)-ethyl]-carbamoyl}-1H-pyrazol-4-yl)-acetic acid ethyl ester

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Technology Process of (1-(2-Chloro-phenyl)-5-(4-chloro-phenyl)-3-{methyl-[(R)-1-(4-trifluoromethyl-phenyl)-ethyl]-carbamoyl}-1H-pyrazol-4-yl)-acetic acid ethyl ester

There total 2 articles about (1-(2-Chloro-phenyl)-5-(4-chloro-phenyl)-3-{methyl-[(R)-1-(4-trifluoromethyl-phenyl)-ethyl]-carbamoyl}-1H-pyrazol-4-yl)-acetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 672906-72-8,574731-05-8
(R)-1-(4-trifluoromethylphenyl)ethylamine N-monomethyl

: 1034265-89-8
1-(2-chloro-phenyl)-5-(4-chloro-phenyl)-4-ethoxycarbonylmethyl-1H-pyrazole-3-carboxylic acid

: 1034265-92-3
(1-(2-Chloro-phenyl)-5-(4-chloro-phenyl)-3-{methyl-[(R)-1-(4-trifluoromethyl-phenyl)-ethyl]-carbamoyl}-1H-pyrazol-4-yl)-acetic acid ethyl ester

Guidance literature:: 1-(2-chloro-phenyl)-5-(4-chloro-phenyl)-4-ethoxycarbonylmethyl-1H-pyrazole-3-carboxylic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 0 - 20 ℃; for 2.5h;

(R)-1-(4-trifluoromethylphenyl)ethylamine N-monomethyl; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃;

Reference yield:

: 1034265-92-3
(1-(2-Chloro-phenyl)-5-(4-chloro-phenyl)-3-{methyl-[(R)-1-(4-trifluoromethyl-phenyl)-ethyl]-carbamoyl}-1H-pyrazol-4-yl)-acetic acid ethyl ester

Guidance literature:

Reference yield:

: 1034265-92-3
(1-(2-Chloro-phenyl)-5-(4-chloro-phenyl)-3-{methyl-[(R)-1-(4-trifluoromethyl-phenyl)-ethyl]-carbamoyl}-1H-pyrazol-4-yl)-acetic acid ethyl ester

: 1034265-97-8
C₃₀H₂₆Cl₂F₃N₃O₄

Guidance literature:: (1-(2-Chloro-phenyl)-5-(4-chloro-phenyl)-3-{methyl-[(R)-1-(4-trifluoromethyl-phenyl)-ethyl]-carbamoyl}-1H-pyrazol-4-yl)-acetic acid ethyl ester; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.5h;

With 2-benzenesulfonyl oxaziridine; In tetrahydrofuran; at -78 ℃; for 2h;

With water; In tetrahydrofuran;