Methyl 4-(benzo[b]thiophen-2-yl)benzoate

Base Information

• Chemical Name: Methyl 4-(benzo[b]thiophen-2-yl)benzoate
• CAS No.: 132932-63-9
• Molecular Formula: C₁₆H₁₂O₂S
• Molecular Weight: 268.336
• DSSTox Substance ID: DTXSID501294237

Synonyms:132932-63-9;Methyl 4-(benzo[b]thiophen-2-yl)benzoate;SCHEMBL732990;JDCUPUFNNLIUHS-UHFFFAOYSA-N;DTXSID501294237;Methyl 4-benzo[b]thien-2-ylbenzoate

Chemical Property of Methyl 4-(benzo[b]thiophen-2-yl)benzoate

Chemical Property:

• XLogP3: 4.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 268.05580079
• Heavy Atom Count: 19
• Complexity: 323

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC(=O)C1=CC=C(C=C1)C2=CC3=CC=CC=C3S2

Technology Process of Methyl 4-(benzo[b]thiophen-2-yl)benzoate

There total 9 articles about Methyl 4-(benzo[b]thiophen-2-yl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

methyl 4-((2-(methylsulfanyl)phenyl)ethynyl)benzoate → 2-(p-methoxycarbonylphenyl)benzothiophene (132932-63-9)

Guidance literature:

With AuOH(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene); acetic acid; In toluene; at 100 ℃; for 20h;

DOI:10.1039/c8ob02196a

Reference yield: 70.0%

methyl 4-iodobenzoate (619-44-3) + Benzo[b]thiophene (95-15-8,11095-43-5) → 2-(p-methoxycarbonylphenyl)benzothiophene (132932-63-9)

Guidance literature:

With 1,1,1,3',3',3'-hexafluoro-propanol; sodium acetate; palladium diacetate; silver(l) oxide; at 50 ℃; for 16h; regioselective reaction;

DOI:10.1021/jacs.8b05361

Reference yield: 66.0%

bis[4-(methoxycarbonyl)phenyl]iodonium trifluoromethanesulfonate (1416276-96-4) + Benzo[b]thiophene (95-15-8,11095-43-5) → 2-(p-methoxycarbonylphenyl)benzothiophene (132932-63-9)

Guidance literature:

With tris(bipyridine)ruthenium(II) dichloride hexahydrate; In acetonitrile; at 25 ℃; for 12h; regioselective reaction; Inert atmosphere; Irradiation; Schlenk technique;

DOI:10.1055/s-0032-1318155

upstream raw materials:

4-methoxycarbonylphenyl bromide

Benzo[b]thiophene

benzo[b]thiophene-2-boronic acid

bis[4-(methoxycarbonyl)phenyl]iodonium trifluoromethanesulfonate

Downstream raw materials:

4-(benzo[b]thiophen-2-yl)benzoic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 132932-63-9 2-(p-methoxycarbonylphenyl)benzothiophene

Send

Send

Metric Ton KG G Pound L ML

Send

Send