5-[2-amino-2-(2,4-difluorophenyl)-1-hydroxyethyl]-1-(2,6-dimethylphenyl)-2(1H)-pyridinone hydrochloride

Base Information

Chemical Name:5-[2-amino-2-(2,4-difluorophenyl)-1-hydroxyethyl]-1-(2,6-dimethylphenyl)-2(1H)-pyridinone hydrochloride
CAS No.:934188-46-2
Molecular Formula:C₂₁H₂₀F₂N₂O₂*ClH
Molecular Weight:406.86
Hs Code.:

Synonyms:5-[2-amino-2-(2,4-difluorophenyl)-1-hydroxyethyl]-1-(2,6-dimethylphenyl)-2(1H)-pyridinone hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-[2-amino-2-(2,4-difluorophenyl)-1-hydroxyethyl]-1-(2,6-dimethylphenyl)-2(1H)-pyridinone hydrochloride

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Technology Process of 5-[2-amino-2-(2,4-difluorophenyl)-1-hydroxyethyl]-1-(2,6-dimethylphenyl)-2(1H)-pyridinone hydrochloride

There total 1 articles about 5-[2-amino-2-(2,4-difluorophenyl)-1-hydroxyethyl]-1-(2,6-dimethylphenyl)-2(1H)-pyridinone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 934188-45-1
(2Z)-1-[1-(4-chloro-2,6-dimethylphenyl)-6-oxo-1,6-dihydro-3-pyridinyl]-2-(2,4-difluorophenyl)-1,2-ethanedione 2-oxime

: 934188-46-2
5-[2-amino-2-(2,4-difluorophenyl)-1-hydroxyethyl]-1-(2,6-dimethylphenyl)-2(1H)-pyridinone hydrochloride

Guidance literature:: With hydrogenchloride; hydrogen; palladium 10% on activated carbon; In methanol; at 20 ℃; for 5h;

Reference yield:

: 5337-03-1
tetrahydro-2H-pyran-4-carboxylic acid

: 934188-46-2
5-[2-amino-2-(2,4-difluorophenyl)-1-hydroxyethyl]-1-(2,6-dimethylphenyl)-2(1H)-pyridinone hydrochloride

: 934188-47-3
N-(1-(2,4-difluorophenyl)-2-[1-(2,6-dimethylphenyl)-6-oxo-1,6-dihydro-3-pyridinyl]-2-hydroxyethyl)tetrahydro-2H-pyran-4-carboxamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 20h;