6-(1,2,3,4-tetrahydronaphthalene)-sulfonyl-N-{7-[3-(N-benzyl-N-methyl)-amino-propoxy]-2,3-dihydro-2,2-dimethyl-benzofuran-5-yl}-amide

Base Information

Chemical Name:6-(1,2,3,4-tetrahydronaphthalene)-sulfonyl-N-{7-[3-(N-benzyl-N-methyl)-amino-propoxy]-2,3-dihydro-2,2-dimethyl-benzofuran-5-yl}-amide
CAS No.:1089187-42-7
Molecular Formula:C₃₁H₃₈N₂O₄S
Molecular Weight:534.72
Hs Code.:

Synonyms:6-(1,2,3,4-tetrahydronaphthalene)-sulfonyl-N-{7-[3-(N-benzyl-N-methyl)-amino-propoxy]-2,3-dihydro-2,2-dimethyl-benzofuran-5-yl}-amide

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Chemical Property of 6-(1,2,3,4-tetrahydronaphthalene)-sulfonyl-N-{7-[3-(N-benzyl-N-methyl)-amino-propoxy]-2,3-dihydro-2,2-dimethyl-benzofuran-5-yl}-amide

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Technology Process of 6-(1,2,3,4-tetrahydronaphthalene)-sulfonyl-N-{7-[3-(N-benzyl-N-methyl)-amino-propoxy]-2,3-dihydro-2,2-dimethyl-benzofuran-5-yl}-amide

There total 2 articles about 6-(1,2,3,4-tetrahydronaphthalene)-sulfonyl-N-{7-[3-(N-benzyl-N-methyl)-amino-propoxy]-2,3-dihydro-2,2-dimethyl-benzofuran-5-yl}-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.1%

: 1089187-33-6
2,2-dimethyl-5-amino-7-[3-(N-methyl-N-benzyl)-amino-propoxy]-2,3-dihydro-benzofuran

: 61551-49-3
5,6,7,8-tetrahydronaphthalene-2-sulfonyl chloride

: 1089187-42-7
6-(1,2,3,4-tetrahydronaphthalene)-sulfonyl-N-{7-[3-(N-benzyl-N-methyl)-amino-propoxy]-2,3-dihydro-2,2-dimethyl-benzofuran-5-yl}-amide

Guidance literature:: With sodium hydroxide; In water; for 6h; Heating / reflux;

Reference yield:

: 2,2-dimethyl-5-nitro-7-[3-(N-methyl-N-benzyl)-amino-propoxy]-2,3-dihydro-benzofuran

: 1089187-42-7
6-(1,2,3,4-tetrahydronaphthalene)-sulfonyl-N-{7-[3-(N-benzyl-N-methyl)-amino-propoxy]-2,3-dihydro-2,2-dimethyl-benzofuran-5-yl}-amide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine / 5%-palladium/activated carbon / ethanol / 23 h / 0 - 20 °C

2: sodium hydroxide / water / 6 h / Heating / reflux

With sodium hydroxide; hydrazine; 5%-palladium/activated carbon; In ethanol; water;