(Z)-3-(4-diphenylaminophenyl)-2-(4'-methylbiphenyl-4-yl)acrylonitrile

Base Information

• Chemical Name: (Z)-3-(4-diphenylaminophenyl)-2-(4'-methylbiphenyl-4-yl)acrylonitrile
• CAS No.: 1254816-54-0
• Molecular Formula: C₃₄H₂₆N₂
• Molecular Weight: 462.594
• Mol file: 1254816-54-0.mol

Synonyms:(Z)-3-(4-diphenylaminophenyl)-2-(4'-methylbiphenyl-4-yl)acrylonitrile

Chemical Property of (Z)-3-(4-diphenylaminophenyl)-2-(4'-methylbiphenyl-4-yl)acrylonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-3-(4-diphenylaminophenyl)-2-(4'-methylbiphenyl-4-yl)acrylonitrile

There total 5 articles about (Z)-3-(4-diphenylaminophenyl)-2-(4'-methylbiphenyl-4-yl)acrylonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

(Z)-2-(4-bromophenyl)-3-(4-(diphenylamine)phenyl)acrylonitrile (1254816-50-6) + 4-methylphenylboronic acid (5720-05-8) → (Z)-3-(4-diphenylaminophenyl)-2-(4'-methylbiphenyl-4-yl)acrylonitrile (1254816-54-0)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,2-dimethoxyethane; ethanol; water; for 4h; Reflux;

DOI:10.1016/j.dyepig.2010.07.010

Reference yield:

bromobenzene (108-86-1,52753-63-6) → (Z)-3-(4-diphenylaminophenyl)-2-(4'-methylbiphenyl-4-yl)acrylonitrile (1254816-54-0)

Guidance literature:

Multi-step reaction with 4 steps

1: palladium diacetate; tris-(o-tolyl)phosphine; sodium t-butanolate / toluene / 110 °C

2: trichlorophosphate

3: sodium methylate / ethanol / 2 h / 20 °C

4: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / 1,2-dimethoxyethane; ethanol; water / 4 h / Reflux

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium methylate; palladium diacetate; sodium carbonate; tris-(o-tolyl)phosphine; sodium t-butanolate; trichlorophosphate; In 1,2-dimethoxyethane; ethanol; water; toluene; 4: Suzuki coupling;

DOI:10.1016/j.dyepig.2010.07.010

Reference yield:

4-(diphenylamino)benzaldehyde (4181-05-9) → (Z)-3-(4-diphenylaminophenyl)-2-(4'-methylbiphenyl-4-yl)acrylonitrile (1254816-54-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium methylate / ethanol / 2 h / 20 °C

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / 1,2-dimethoxyethane; ethanol; water / 4 h / Reflux

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium methylate; sodium carbonate; In 1,2-dimethoxyethane; ethanol; water; 2: Suzuki coupling;

DOI:10.1016/j.dyepig.2010.07.010

upstream raw materials:

bromobenzene

(Z)-2-(4-bromophenyl)-3-(4-(diphenylamine)phenyl)acrylonitrile

4-methylphenylboronic acid

N,N-diphenylaminobenzene