5-Isoquinolinamine,8-bromo-(9CI)

Base Information

• Chemical Name: 5-Isoquinolinamine,8-bromo-(9CI)
• CAS No.: 90721-34-9
• Molecular Formula: C9H7 Br N2
• Molecular Weight: 223.07
• Hs Code.: 2933499090
• Mol file: 90721-34-9.mol

Synonyms:Isoquinoline,5-amino-8-bromo- (7CI); 8-Bromoisoquinolin-5-amine

Chemical Property of 5-Isoquinolinamine,8-bromo-(9CI)

Chemical Property:

• PSA: 38.91000
• LogP: 3.16070
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

NLT 98% ^*data from raw suppliers

8-Bromoisoquinolin-5-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Isoquinolinamine,8-bromo-(9CI)

There total 3 articles about 5-Isoquinolinamine,8-bromo-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

8-bromo-5-nitroisoquinoline (252861-41-9) → 8-bromoisoquinolin-5-amine (90721-34-9)

Guidance literature:

With iron; ammonium chloride; In methanol; water; at 50 ℃; for 2h; Inert atmosphere;

Reference yield: 35.0%

isoquinolin-5-ylamine (1125-60-6) → 8-bromoisoquinolin-5-amine (90721-34-9)

Guidance literature:

With bromine; aluminium trichloride;

Reference yield:

→ 8-bromoisoquinolin-5-amine (90721-34-9)

Guidance literature:

5-Amino-isochinolin, ca. 2.9 Mol AlCl3, 0.5 Mol Br2-Dampf (80grad);

upstream raw materials:

isoquinolin-5-ylamine

8-bromo-5-nitroisoquinoline

Downstream raw materials:

N-(8-bromoisoquinolin-5-yl)-N'-(2,4-dichlorobenzyl)urea

N-(8-bromoisoquinolin-5-yl)-N'-(2,4-dichlorobenzyl)urea hydrochloride

Refernces

• 1、 -. "Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor". . . Retrieved 2008/06/13.
• 2、 -. "Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor". . . Retrieved 2008/06/13.