methyl trans-4-{4-[6-(aminocarbonyl)-3-methylpyrazin-2-yl]phenyl}-cyclohexanecarboxylate

Base Information

Chemical Name:methyl trans-4-{4-[6-(aminocarbonyl)-3-methylpyrazin-2-yl]phenyl}-cyclohexanecarboxylate
CAS No.:1166831-51-1
Molecular Formula:C₂₀H₂₃N₃O₃
Molecular Weight:353.421
Hs Code.:

Synonyms:methyl trans-4-{4-[6-(aminocarbonyl)-3-methylpyrazin-2-yl]phenyl}-cyclohexanecarboxylate

Suppliers and Price of methyl trans-4-{4-[6-(aminocarbonyl)-3-methylpyrazin-2-yl]phenyl}-cyclohexanecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl trans-4-{4-[6-(aminocarbonyl)-3-methylpyrazin-2-yl]phenyl}-cyclohexanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl trans-4-{4-[6-(aminocarbonyl)-3-methylpyrazin-2-yl]phenyl}-cyclohexanecarboxylate

There total 4 articles about methyl trans-4-{4-[6-(aminocarbonyl)-3-methylpyrazin-2-yl]phenyl}-cyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: 1166831-52-2
6-{4-[trans-4-(methoxycarbonyl)cyclohexyl]phenyl}-5-methylpyrazine-2-carboxylic acid

: 1166831-51-1
methyl trans-4-{4-[6-(aminocarbonyl)-3-methylpyrazin-2-yl]phenyl}-cyclohexanecarboxylate

Guidance literature:: With 4-methyl-morpholine; ammonia; chloroformic acid ethyl ester; In methanol; dichloromethane; at 0 ℃; for 1h; Heating;

Reference yield:

: methyl trans-4-[4-(2-bromopropanoyl)phenyl]cyclohexanecarboxylate

: 1166831-51-1
methyl trans-4-{4-[6-(aminocarbonyl)-3-methylpyrazin-2-yl]phenyl}-cyclohexanecarboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydroxide / water; N,N-dimethyl-formamide / 0.67 h

2: Dess-Martin periodane / dichloromethane / 1 h

3: triethylamine / methanol / 48 h

4: 4-methyl-morpholine; ammonia; chloroformic acid ethyl ester / methanol; dichloromethane / 1 h / 0 °C / Heating

With 4-methyl-morpholine; ammonia; chloroformic acid ethyl ester; Dess-Martin periodane; triethylamine; sodium hydroxide; In methanol; dichloromethane; water; N,N-dimethyl-formamide;

Reference yield:

: 1166831-53-3
methyl trans-4-(4-pyruvoylphenyl)cyclohexanecarboxylate

: 1166831-51-1
methyl trans-4-{4-[6-(aminocarbonyl)-3-methylpyrazin-2-yl]phenyl}-cyclohexanecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / methanol / 48 h

2: 4-methyl-morpholine; ammonia; chloroformic acid ethyl ester / methanol; dichloromethane / 1 h / 0 °C / Heating

With 4-methyl-morpholine; ammonia; chloroformic acid ethyl ester; triethylamine; In methanol; dichloromethane;