7-Oxo-7-(5-phenyl-thiophen-2-yl)-heptanoic acid ethyl ester

Base Information

• Chemical Name: 7-Oxo-7-(5-phenyl-thiophen-2-yl)-heptanoic acid ethyl ester
• CAS No.: 142259-74-3
• Molecular Formula: C₁₉H₂₂O₃S
• Molecular Weight: 330.448
• Mol file: 142259-74-3.mol

Synonyms:7-Oxo-7-(5-phenyl-thiophen-2-yl)-heptanoic acid ethyl ester

Chemical Property of 7-Oxo-7-(5-phenyl-thiophen-2-yl)-heptanoic acid ethyl ester

Chemical Property:

Purity/Quality:

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Technology Process of 7-Oxo-7-(5-phenyl-thiophen-2-yl)-heptanoic acid ethyl ester

There total 1 articles about 7-Oxo-7-(5-phenyl-thiophen-2-yl)-heptanoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.5%

ethyl 6-(chloroformyl)hexanoate (14794-32-2) + 2-phenylthiophene (825-55-8) → 7-Oxo-7-(5-phenyl-thiophen-2-yl)-heptanoic acid ethyl ester (142259-74-3)

Guidance literature:

With tin(IV) chloride; In 1,2-dichloro-ethane; for 1h; Ambient temperature;

DOI:10.1021/jm00095a010

Reference yield: 34.3%

7-Oxo-7-(5-phenyl-thiophen-2-yl)-heptanoic acid ethyl ester (142259-74-3) → 7-(5-phenyl-2-thienyl)heptanoic acid (142260-09-1)

Guidance literature:

With potassium hydroxide; hydrazine hydrate; In various solvent(s); at 210 ℃; for 4h;

DOI:10.1021/jm00095a010

upstream raw materials:

ethyl 6-(chloroformyl)hexanoate

2-phenylthiophene

Downstream raw materials:

7-(5-phenyl-2-thienyl)heptanoic acid