2-(2,5-dimethyl-1H-pyrrol-1-yl)-3-phenylpropionic acid tert-butyl ester

Base Information

Chemical Name:2-(2,5-dimethyl-1H-pyrrol-1-yl)-3-phenylpropionic acid tert-butyl ester
CAS No.:1325726-71-3
Molecular Formula:C₁₉H₂₅NO₂
Molecular Weight:299.413
Hs Code.:

Synonyms:2-(2,5-dimethyl-1H-pyrrol-1-yl)-3-phenylpropionic acid tert-butyl ester

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Chemical Property of 2-(2,5-dimethyl-1H-pyrrol-1-yl)-3-phenylpropionic acid tert-butyl ester

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Technology Process of 2-(2,5-dimethyl-1H-pyrrol-1-yl)-3-phenylpropionic acid tert-butyl ester

There total 1 articles about 2-(2,5-dimethyl-1H-pyrrol-1-yl)-3-phenylpropionic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 15100-75-1,75898-47-4
L-phenylalanine tert-butyl ester hydrochloride

: 110-13-4
2,5-hexanedione

: 1325726-71-3
2-(2,5-dimethyl-1H-pyrrol-1-yl)-3-phenylpropionic acid tert-butyl ester

Guidance literature:: L-phenylalanine tert-butyl ester hydrochloride; With triethylamine; In tetrahydrofuran; at 20 ℃; for 0.5h;

2,5-hexanedione; With iodine; In tetrahydrofuran; at 20 ℃; for 24h; optical yield given as %ee; enantioselective reaction;
DOI:10.1007/s10593-011-0739-7