N₁-{(1S,2R)-1-benzyl-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}-5-cyano-N₃,N₃-dipropylisophthalamide hydrochloride

Base Information

• Chemical Name: N₁-{(1S,2R)-1-benzyl-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}-5-cyano-N₃,N₃-dipropylisophthalamide hydrochloride
• CAS No.: 388064-66-2
• Molecular Formula: C₃₃H₄₀N₄O₄*ClH
• Molecular Weight: 593.166

Synonyms:N₁-{(1S,2R)-1-benzyl-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}-5-cyano-N₃,N₃-dipropylisophthalamide hydrochloride

Chemical Property of N₁-{(1S,2R)-1-benzyl-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}-5-cyano-N₃,N₃-dipropylisophthalamide hydrochloride

Chemical Property:

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Technology Process of N₁-{(1S,2R)-1-benzyl-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}-5-cyano-N₃,N₃-dipropylisophthalamide hydrochloride

There total 1 articles about N₁-{(1S,2R)-1-benzyl-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}-5-cyano-N₃,N₃-dipropylisophthalamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl (2R,3S)-3-({3-cyano-5-[(dipropylamino)carbonyl]benzoyl}amino)-2-hydroxy-4-phenylbutyl-(3-methoxybenzyl)carbamate (388071-39-4) → N1-{(1S,2R)-1-benzyl-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}-5-cyano-N3,N3-dipropylisophthalamide hydrochloride (388064-66-2)

Guidance literature:

With hydrogenchloride; In methanol; dichloromethane; for 8h;

upstream raw materials:

tert-butyl (2R,3S)-3-({3-cyano-5-[(dipropylamino)carbonyl]benzoyl}amino)-2-hydroxy-4-phenylbutyl-(3-methoxybenzyl)carbamate

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