Technology Process of 5-tert-butyl-2-p-tolylbenzofuran
There total 4 articles about 5-tert-butyl-2-p-tolylbenzofuran which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
water;
at 110 ℃;
for 2h;
Microwave irradiation;
Inert atmosphere;
Green chemistry;
DOI:10.1016/j.tet.2014.04.005
- Guidance literature:
-
Multi-step reaction with 3 steps
1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / tetrahydrofuran / 50 °C / Inert atmosphere
2: hydrogenchloride / methanol; water / Reflux; Inert atmosphere
3: potassium carbonate / water / 2 h / 110 °C / Microwave irradiation; Inert atmosphere; Green chemistry
With
hydrogenchloride; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; potassium carbonate; triethylamine;
In
tetrahydrofuran; methanol; water;
1: |Sonogashira Cross-Coupling;
DOI:10.1016/j.tet.2014.04.005
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium hydride / N,N-dimethyl-formamide / 20 °C / Inert atmosphere; Cooling with ice
2: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / tetrahydrofuran / 50 °C / Inert atmosphere
3: hydrogenchloride / methanol; water / Reflux; Inert atmosphere
4: potassium carbonate / water / 2 h / 110 °C / Microwave irradiation; Inert atmosphere; Green chemistry
With
hydrogenchloride; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; sodium hydride; potassium carbonate; triethylamine;
In
tetrahydrofuran; methanol; water; N,N-dimethyl-formamide;
2: |Sonogashira Cross-Coupling;
DOI:10.1016/j.tet.2014.04.005
