2-azidoethyl α-5-acetamido-9-(biphenylcarbonylamino)-3,5,9-trideoxy-D-glycero-2-nonulosonic acid-pyranosyl-(2->3)-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-glucopyranoside

Base Information

• Chemical Name: 2-azidoethyl α-5-acetamido-9-(biphenylcarbonylamino)-3,5,9-trideoxy-D-glycero-2-nonulosonic acid-pyranosyl-(2->3)-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-glucopyranoside
• CAS No.: 1019642-47-7
• Molecular Formula: C₄₀H₅₄N₆O₁₉
• Molecular Weight: 922.898
• Mol file: 1019642-47-7.mol

Synonyms:2-azidoethyl α-5-acetamido-9-(biphenylcarbonylamino)-3,5,9-trideoxy-D-glycero-2-nonulosonic acid-pyranosyl-(2->3)-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-glucopyranoside

Chemical Property of 2-azidoethyl α-5-acetamido-9-(biphenylcarbonylamino)-3,5,9-trideoxy-D-glycero-2-nonulosonic acid-pyranosyl-(2->3)-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-azidoethyl α-5-acetamido-9-(biphenylcarbonylamino)-3,5,9-trideoxy-D-glycero-2-nonulosonic acid-pyranosyl-(2->3)-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-glucopyranoside

There total 2 articles about 2-azidoethyl α-5-acetamido-9-(biphenylcarbonylamino)-3,5,9-trideoxy-D-glycero-2-nonulosonic acid-pyranosyl-(2->3)-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

C24H28N2O9 + 2-azidoethyl (β-D-galactopyranosyl)-(1->4)-O-2-acetamido-2-deoxy-β-D-glucopyranoside (338971-38-3) → 2-azidoethyl α-5-acetamido-9-(biphenylcarbonylamino)-3,5,9-trideoxy-D-glycero-2-nonulosonic acid-pyranosyl-(2->3)-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-glucopyranoside (1019642-47-7)

Guidance literature:

With CMP-sialic acid synthetase; α2?6-sialyltransferase hST6Gal-I; cytidine triphosphate; magnesium chloride; In aq. buffer; at 37 ℃; pH=8.5; Reagent/catalyst; Enzymatic reaction;

DOI:10.1021/jacs.7b03208

Reference yield: 78.0%

C24H28N2O9 (936547-18-1) + uridine-5'-diphosphoglucose (952585-00-1) + 2'-azidoethyl 2-acetamido-2-deoxy-β-D-glucopyranoside (142072-12-6) → 2-azidoethyl α-5-acetamido-9-(biphenylcarbonylamino)-3,5,9-trideoxy-D-glycero-2-nonulosonic acid-pyranosyl-(2->3)-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-glucopyranoside (1019642-47-7)

Guidance literature:

With CMPNeu₅Ac synthetase; cytidine 5'-triphosphate disodium salt; Galβ1-4-GlcNaC α2-6-sialyltransferase; β1-4-galactotransferase-galactoepimerase fusion enzyme; In various solvent(s); at 20 ℃; for 48h;

DOI:10.1021/ja077801n

Reference yield:

2-azidoethyl α-5-acetamido-9-(biphenylcarbonylamino)-3,5,9-trideoxy-D-glycero-2-nonulosonic acid-pyranosyl-(2->3)-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-glucopyranoside (1019642-47-7) → 2-aminoethyl 5-acetamido-9-(4-biphenylcarbonylamino)-3,5,9-trideoxy-α-D-glycero-D-galacto-2-nonulopyranosylonate-(2-6)-O-β-D-galactopyranosyl-(1-4)-O-2-acetamido-2-deoxy-β-D-glucopyranoside (936547-19-2)

Guidance literature:

With trimethylphosphane; In tetrahydrofuran; water; at 20 ℃; for 2h;

DOI:10.1021/jacs.7b03208

upstream raw materials:

C₂₄H₂₈N₂O₉

uridine-5'-diphosphoglucose

2'-azidoethyl 2-acetamido-2-deoxy-β-D-glucopyranoside

2-azidoethyl (β-D-galactopyranosyl)-(1->4)-O-2-acetamido-2-deoxy-β-D-glucopyranoside

Downstream raw materials:

2-aminoethyl 5-acetamido-9-(4-biphenylcarbonylamino)-3,5,9-trideoxy-α-D-glycero-D-galacto-2-nonulopyranosylonate-(2-6)-O-β-D-galactopyranosyl-(1-4)-O-2-acetamido-2-deoxy-β-D-glucopyranoside