(S_P)-(-)-menthyl methylphenylphosphine oxide

Base Information

• Chemical Name: (S_P)-(-)-menthyl methylphenylphosphine oxide
• CAS No.: 65440-76-8
• Molecular Formula: C₁₇H₂₇OP
• Molecular Weight: 278.375
• Mol file: 65440-76-8.mol

Synonyms:(S_P)-(-)-menthyl methylphenylphosphine oxide

Chemical Property of (S_P)-(-)-menthyl methylphenylphosphine oxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S_P)-(-)-menthyl methylphenylphosphine oxide

There total 6 articles about (S_P)-(-)-menthyl methylphenylphosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(SP)-Menthylmethylphenylphosphine (65440-73-5,65440-74-6) → (SP)-(-)-menthyl methylphenylphosphine oxide (65440-76-8)

Guidance literature:

With dihydrogen peroxide; In benzene; at 23 ℃; for 18h;

DOI:10.1021/jo01306a030

Reference yield:

RP-(-)-menthyl phenylphosphine oxide → (SP)-(-)-menthyl methylphenylphosphine oxide (65440-76-8)

Guidance literature:

Multi-step reaction with 2 steps

1: N-chloro-succinimide / tetrahydrofuran / 0.03 h / 0 °C / Inert atmosphere; Schlenk technique

2: tetrahydrofuran; diethyl ether / 16 h / 20 °C / Inert atmosphere; Schlenk technique

With N-chloro-succinimide; In tetrahydrofuran; diethyl ether;

DOI:10.1021/acs.orglett.7b02667

Reference yield:

L-menthylphenylchlorophosphine (55266-95-0,103667-69-2,103667-70-5) → (SP)-(-)-menthyl methylphenylphosphine oxide (65440-76-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 3-chloro-benzenecarboperoxoic acid / tetrahydrofuran / Inert atmosphere; Schlenk technique

2: tetrahydrofuran; diethyl ether / 16 h / 20 °C / Inert atmosphere; Schlenk technique

With 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; diethyl ether;

DOI:10.1021/acs.orglett.7b02667

upstream raw materials:

(S_P)-Menthylmethylphenylphosphine

Neomenthylmethyldiphenylphosphonium Iodide

(R_P)-Menthylmethylphenylphosphine Oxide

L-menthylphenylchlorophosphine

Downstream raw materials:

(R_P)-Menthylmethylphenylphosphine Oxide

(S_P)-Menthylmethylphenylphosphine