(E)-1-(1,1,2,2,3,3,4,4,5,5,6,6,6-Tridecafluorohexyl)-2-phenylsulfonylethene

Base Information

• Chemical Name: (E)-1-(1,1,2,2,3,3,4,4,5,5,6,6,6-Tridecafluorohexyl)-2-phenylsulfonylethene
• CAS No.: 291541-43-0
• Molecular Formula: C₁₄H₇F₁₃O₂S
• Molecular Weight: 486.254
• Mol file: 291541-43-0.mol

Synonyms:(E)-1-(1,1,2,2,3,3,4,4,5,5,6,6,6-Tridecafluorohexyl)-2-phenylsulfonylethene

Chemical Property of (E)-1-(1,1,2,2,3,3,4,4,5,5,6,6,6-Tridecafluorohexyl)-2-phenylsulfonylethene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-1-(1,1,2,2,3,3,4,4,5,5,6,6,6-Tridecafluorohexyl)-2-phenylsulfonylethene

There total 1 articles about (E)-1-(1,1,2,2,3,3,4,4,5,5,6,6,6-Tridecafluorohexyl)-2-phenylsulfonylethene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

diethyl phenylsulfonylmethylphosphonate (56069-39-7) + perfluorohexyl aldehyde (63967-41-9) → (E)-1-(1,1,2,2,3,3,4,4,5,5,6,6,6-Tridecafluorohexyl)-2-phenylsulfonylethene (291541-43-0)

Guidance literature:

diethyl phenylsulfonylmethylphosphonate; With n-butyllithium; In tetrahydrofuran; hexane; at 20 ℃; for 0.5h; Irradiation;

perfluorohexyl aldehyde; In tetrahydrofuran; hexane; at 20 ℃; for 0.5h;

DOI:10.1016/S0022-1139(00)00212-8

Reference yield: 40.0%

Methyl 6-azido-2-O-cyclohexylcarbamoyl-6-deoxy-3,4-O-(2,2,2-trichloroethylidene)-α-D-altropyranoside (291541-45-2) + (E)-1-(1,1,2,2,3,3,4,4,5,5,6,6,6-Tridecafluorohexyl)-2-phenylsulfonylethene (291541-43-0) → 1-[Methyl 2-O-cyclohexylcarbamoyl-6-deoxy-3,4-O-(2,2,2-trichloroethylidene)-α-D-altropyranosido-6-yl]-4-perfluorohexyl-1,2,3-triazole (291541-50-9)

Guidance literature:

In toluene; for 32h; Heating;

DOI:10.1016/S0022-1139(00)00212-8

Reference yield:

(E)-1-(1,1,2,2,3,3,4,4,5,5,6,6,6-Tridecafluorohexyl)-2-phenylsulfonylethene (291541-43-0) → 1-(Methyl 2-O-cyclohexylcarbamoyl-6-deoxy-α-D-altropyranosido-6-yl)-4-perfluorohexyl-1,2,3-triazole (291541-56-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 40 percent / toluene / 32 h / Heating

2: 69 percent / Bu₃SnH; AIBN / toluene / 10 h / 75 °C

3: 71 percent / aq. TFA / 7 h / 50 °C

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; trifluoroacetic acid; In toluene; 1: Cycloaddition / 2: Reduction / 3: Hydrolysis;

DOI:10.1016/S0022-1139(00)00212-8

upstream raw materials:

diethyl phenylsulfonylmethylphosphonate

perfluorohexyl aldehyde

Downstream raw materials:

1-[Methyl 2-O-cyclohexylcarbamoyl-6-deoxy-3,4-O-(2,2,2-trichloroethylidene)-α-D-altropyranosido-6-yl]-4-perfluorohexyl-1,2,3-triazole

1-(Methyl 2-O-cyclohexylcarbamoyl-6-deoxy-α-D-altropyranosido-6-yl)-4-perfluorohexyl-1,2,3-triazole

1-(Methyl 2-O-cyclohexylcarbamoyl-6-deoxy-3,4-O-ethylidene-α-D-altropyranosido-6-yl)-4-perfluorohexyl-1,2,3-triazole