N-[2-(tert-butyl)-4-penten-1-oxy]-4-(p-chlorophenyl)thiazole-2(3H)-thione

Base Information

• Chemical Name: N-[2-(tert-butyl)-4-penten-1-oxy]-4-(p-chlorophenyl)thiazole-2(3H)-thione
• CAS No.: 352200-58-9
• Molecular Formula: C₁₈H₂₂ClNOS₂
• Molecular Weight: 367.964
• Mol file: 352200-58-9.mol

Synonyms:N-[2-(tert-butyl)-4-penten-1-oxy]-4-(p-chlorophenyl)thiazole-2(3H)-thione

Chemical Property of N-[2-(tert-butyl)-4-penten-1-oxy]-4-(p-chlorophenyl)thiazole-2(3H)-thione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[2-(tert-butyl)-4-penten-1-oxy]-4-(p-chlorophenyl)thiazole-2(3H)-thione

There total 1 articles about N-[2-(tert-butyl)-4-penten-1-oxy]-4-(p-chlorophenyl)thiazole-2(3H)-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-(1,1-dimethylethyl)-4-penten-1-yl p-toluenesulfonate (132621-52-4) + N-(hydroxy)-4-(p-chlorophenyl)thiazole-2(3H)-thione tetrabutylammonium salt → N-[2-(tert-butyl)-4-penten-1-oxy]-4-(p-chlorophenyl)thiazole-2(3H)-thione (352200-58-9)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃; for 144h;

DOI:10.1039/b611473c

Reference yield:

tri-n-butyl-tin hydride (688-73-3) + N-[2-(tert-butyl)-4-penten-1-oxy]-4-(p-chlorophenyl)thiazole-2(3H)-thione (352200-58-9) → 2-(tributylstannyl)sulfanyl-4-(p-chlorophenyl)thiazole (227082-35-1)

Guidance literature:

In further solvent(s); byproducts: (CH3)3CC4H6O(CH3), CH2CHCH2CH(C(CH3)3)CHO, CH2CHCH2CH(C(CH3)3)CH2OH; other Radiation; addn. of 2-2.5 equiv. of tin compd. to soln. of thiazole deriv. in C6H5CF3, microwave irradiating (2.45 GHz, 500 W) for 2.5 min at 80°C; detected by 1H NMR;

DOI:10.1039/b603480b

Reference yield:

N-[2-(tert-butyl)-4-penten-1-oxy]-4-(p-chlorophenyl)thiazole-2(3H)-thione (352200-58-9) → C18H22ClNOS2

Guidance literature:

at 8 ℃; for 17532h; Neat (no solvent);

DOI:10.1002/ejoc.200900069

upstream raw materials:

2-(1,1-dimethylethyl)-4-penten-1-yl p-toluenesulfonate

Downstream raw materials:

2-(tributylstannyl)sulfanyl-4-(p-chlorophenyl)thiazole