(acrylyloxy)-1,4-tetramethylene 4-<7-(4-hydroxyphenyl)heptylidene>benzoate

Base Information

• Chemical Name: (acrylyloxy)-1,4-tetramethylene 4-<7-(4-hydroxyphenyl)heptylidene>benzoate
• CAS No.: 162380-35-0
• Molecular Formula: C₂₇H₃₄O₅
• Molecular Weight: 438.564
• Mol file: 162380-35-0.mol

Synonyms:(acrylyloxy)-1,4-tetramethylene 4-<7-(4-hydroxyphenyl)heptylidene>benzoate

Chemical Property of (acrylyloxy)-1,4-tetramethylene 4-<7-(4-hydroxyphenyl)heptylidene>benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (acrylyloxy)-1,4-tetramethylene 4-<7-(4-hydroxyphenyl)heptylidene>benzoate

There total 6 articles about (acrylyloxy)-1,4-tetramethylene 4-<7-(4-hydroxyphenyl)heptylidene>benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(acrylyloxy)-1,4-tetramethylene 4-<7-<4-<(dimethylthexylsilyl)oxy>phenyl>heptylidene>benzoate (162380-34-9) → (acrylyloxy)-1,4-tetramethylene 4-<7-(4-hydroxyphenyl)heptylidene>benzoate (162380-35-0)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at -78 ℃; for 1.33333h;

DOI:10.1021/ja00124a005

Reference yield:

4-hydroxybutyl acrylate (2478-10-6,29086-87-1) → (acrylyloxy)-1,4-tetramethylene 4-<7-(4-hydroxyphenyl)heptylidene>benzoate (162380-35-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 88.2 percent / DPTS, DIPC / CH₂Cl₂ / 25 h

2: TBAF / tetrahydrofuran / 1.33 h / -78 °C

With bis-2-propyl carbonate; tetrabutyl ammonium fluoride; 4-(dimethylamino)pyridinium tosylate; In tetrahydrofuran; dichloromethane;

DOI:10.1021/ja00124a005

Reference yield:

p-Toluic acid (99-94-5) → (acrylyloxy)-1,4-tetramethylene 4-<7-(4-hydroxyphenyl)heptylidene>benzoate (162380-35-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) potassium tert-butoxide, LDA / 1.) THF, hexane, -78 deg C, 4 h, 2.) THF, hexane, from -78 deg C to 0 deg C, 2.5 h

2: 88.2 percent / DPTS, DIPC / CH₂Cl₂ / 25 h

3: TBAF / tetrahydrofuran / 1.33 h / -78 °C

With bis-2-propyl carbonate; potassium tert-butylate; tetrabutyl ammonium fluoride; 4-(dimethylamino)pyridinium tosylate; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane;

DOI:10.1021/ja00124a005

upstream raw materials:

(acrylyloxy)-1,4-tetramethylene 4-<7-<4-<(dimethylthexylsilyl)oxy>phenyl>heptylidene>benzoate

4-hydroxybutyl acrylate

p-Toluic acid

6-{4-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-phenyl}-hexan-1-ol