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Technology Process of (±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanolhydrochloride

(±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanolhydrochloride

Base Information
  • Chemical Name:(±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanolhydrochloride
  • CAS No.:72795-01-8
  • Molecular Formula:C17H27 N O2 . Cl H
  • Molecular Weight:313.86272
  • Hs Code.:
  • Mol file:72795-01-8.mol
(±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanolhydrochloride

Synonyms:2-Butanol,1-[(2,3-dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-,hydrochloride, (R*,R*)-; ICI 111581; ICI 118551 hydrochloride

Suppliers and Price of (±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanolhydrochloride
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • ICI 118,551 hydrochloride
  • 10mg
  • $ 180.00
  • TRC
  • ICI 118,551 hydrochloride
  • 5mg
  • $ 140.00
  • Sigma-Aldrich
  • ICI 118,551 hydrochloride ≥98% (HPLC), powder
  • 5mg
  • $ 212.00
  • Sigma-Aldrich
  • ICI 118,551 hydrochloride ≥98% (HPLC), powder
  • 25mg
  • $ 754.00
  • DC Chemicals
  • ICI-118551 >98%
  • 1 g
  • $ 1500.00
  • ChemScene
  • ICI 118,551 hydrochloride 99.64%
  • 10mg
  • $ 96.00
  • ChemScene
  • ICI 118,551 hydrochloride 99.64%
  • 50mg
  • $ 300.00
  • ChemScene
  • ICI 118,551 hydrochloride 99.64%
  • 100mg
  • $ 540.00
  • Cayman Chemical
  • ICI 118551 (hydrochloride) ≥99%
  • 50mg
  • $ 548.00
  • Cayman Chemical
  • ICI 118551 (hydrochloride) ≥99%
  • 10mg
  • $ 129.00
Total 20 raw suppliers
Chemical Property of (±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanolhydrochloride
Chemical Property:
  • PSA：41.49000 
  • LogP:3.80280 
  • Storage Temp.:Store at RT 
Purity/Quality:

97% *data from raw suppliers

ICI 118,551 hydrochloride *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Description ICI 118551 is a potent, selective antagonist of the β2-adrenergic receptor (Ki = 0.7 nM for the β2receptor, compared with 49.5 and 611 nM for β1 and β3 receptors, respectively). It is active in vivo and is often used to evaluate the actions of adrenergic receptor agonists.
  • Uses ICI 118,551 hydrochloride has been used:to block β-adrenergic signaling in various experimentsto counteract degradation by endogenous T-lymphocyte monoamine oxidasesto determine the specific receptor subtype necessary for isoproterenol to induce up-regulation of gene transcripts The (R,R)-enantiomer The (R,R)-enantiomer of ICI 118551 as highly selective β2-adrenoceptor antagonist. The S,S-enantiomer is the most potent.
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