N-(4-bromo-2-nitro-6-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide

Base Information

• Chemical Name: N-(4-bromo-2-nitro-6-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide
• CAS No.: 1155800-52-4
• Molecular Formula: C₉H₃BrF₆N₂O₃
• Molecular Weight: 381.029

Synonyms:N-(4-bromo-2-nitro-6-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide

Chemical Property of N-(4-bromo-2-nitro-6-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

4-Bromo-2-nitro-6-(trifluoromethyl)trifluoroacetanilide -% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
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MSDS Files:

SDS file from LookChem

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Technology Process of N-(4-bromo-2-nitro-6-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide

There total 1 articles about N-(4-bromo-2-nitro-6-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

N-(4-bromo-2-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide (218288-13-2) → N-(4-bromo-2-nitro-6-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide (1155800-52-4)

Guidance literature:

With trifluorormethanesulfonic acid; nitric acid; In dichloromethane; water; at 20 ℃; for 20h; Large scale reaction;

DOI:10.1021/op9000498

Reference yield: 100.0%

N-(4-bromo-2-nitro-6-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide (1155800-52-4) → 4-bromo-2-nitro-6-(trifluoromethyl)aniline hydrochloride

Guidance literature:

With hydrogenchloride; In ethanol; at 76 ℃; for 120h;

DOI:10.1021/op9000498

Reference yield: 43.0%

N-(4-bromo-2-nitro-6-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide (1155800-52-4) → 4-bromo-2-nitro-6-trilfuoromethyl-phenylamine (157026-18-1)

Guidance literature:

With water; potassium carbonate; In methanol; at 20 ℃; for 4h; Large scale reaction;

DOI:10.1021/op9000498

upstream raw materials:

N-(4-bromo-2-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide

Downstream raw materials:

4-bromo-2-nitro-6-trilfuoromethyl-phenylamine

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